Evidence map›Paper›PMID 28694929›Full record

ArticleWorld journal of diabetes2017

Statin use and cognitive function in middle-aged adults with type 1 diabetes.

Karen A Nunley, Trevor J Orchard, Christopher M Ryan, Rachel Miller, Tina Costacou, Caterina Rosano

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of diabetes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Karen A NunleyKaren A Nunley, Trevor J Orchard, Christopher M Ryan, Rachel Miller, Tina Costacou, Caterina Rosano, Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, United States.
Trevor J OrchardKaren A Nunley, Trevor J Orchard, Christopher M Ryan, Rachel Miller, Tina Costacou, Caterina Rosano, Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, United States.
Christopher M RyanKaren A Nunley, Trevor J Orchard, Christopher M Ryan, Rachel Miller, Tina Costacou, Caterina Rosano, Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, United States.
Rachel MillerKaren A Nunley, Trevor J Orchard, Christopher M Ryan, Rachel Miller, Tina Costacou, Caterina Rosano, Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, United States.
Tina CostacouKaren A Nunley, Trevor J Orchard, Christopher M Ryan, Rachel Miller, Tina Costacou, Caterina Rosano, Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, United States.
Caterina RosanoKaren A Nunley, Trevor J Orchard, Christopher M Ryan, Rachel Miller, Tina Costacou, Caterina Rosano, Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15213, United States.
Creative Research Enterprises (United States) · USUniversity of Pittsburgh · US

Funding

VARIABILITY, STABILITY & SMOOTHNESS OF WALKINGP30AG024827 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Caterina Rosano · 2004 to 2026
$28.6M
Epidemiology of Diabetes Complications (EDC) Phase II: renewalR37DK034818 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ORCHARD, TREVOR J. · 2009 to 2018
$6.5M
Imaging biomarkers of accelerated brain aging in Type-1 DiabetesR01DK089028 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ROSANO, CATERINA · 2010 to 2013
$2.3M
Oxidative insults, antioxidative responses and type 1 diabetes complicationsR21DK082900 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COSTACOU, TINA · 2009 to 2010
$409k
NIA NIH HHS P30 AG024827NIDDK NIH HHS R01 DK089028NIDDK NIH HHS R21 DK082900NIDDK NIH HHS R37 DK034818
6 · The paper itself

Abstract

aimTo test associations between statin use and cognitive impairment in adults with childhood-onset type 1 diabetes (T1D).

methodsIn 2010-13,

resultsOf the 108 participants, 51 reported never using statins. Median duration of statin use among the 57 ever users was 6 years. These 57 ever statin users were split to create two groups (≤ or > median years of statin use): 1-6 years (

conclusionStatin use was associated with cognitive impairment, particularly affecting memory, in these middle-aged adults with childhood-onset T1D, whom at this age, should not yet manifest age-related memory deficits.

Indexed as

Cognitive impairmentCohort studyMemoryStatin useType 1 diabetes

Identifiers

PMID28694929
PMCPMC5483427
OpenAlexW2758713450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.