Evidence map›Paper›PMID 28694919›Full record

ArticleInternational journal of physiology, pathophysiology and pharmacology2017

8-pCPT-cGMP prevents mitochondrial depolarization and improves the outcome of steatotic partial liver transplantation.

Qinlong Liu, Hasibur Rehman, Yasodha Krishnasamy, John J Lemasters, Zhi Zhong

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of physiology, pathophysiology and pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. UPROrphanet journal of rare diseases · 2022
    Article
  2. Actually Seeing What Is Going on - Intravital Microscopy in Tissue Engineering.Frontiers in bioengineering and biotechnology · 2021
    Review
  3. Regulation of mitochondria function by natriuretic peptides.American journal of physiology. Renal physiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 4 countries.

Qinlong LiuDepartment of Drug Discovery & Biomedical Sciences, Medical University of South CarolinaCharleston 29425, SC, USA.
Hasibur RehmanDepartment of Drug Discovery & Biomedical Sciences, Medical University of South CarolinaCharleston 29425, SC, USA.
Yasodha KrishnasamyDepartment of Drug Discovery & Biomedical Sciences, Medical University of South CarolinaCharleston 29425, SC, USA.
John J LemastersDepartment of Drug Discovery & Biomedical Sciences, Medical University of South CarolinaCharleston 29425, SC, USA.
Zhi ZhongDepartment of Drug Discovery & Biomedical Sciences, Medical University of South CarolinaCharleston 29425, SC, USA.
Medical University of South Carolina · US

Funding

Translational Science Laboratory Shared ResourceP30CA138313 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI Jian Ouyang · 2009 to 2026
$42.7M
LIVER PRESERVATION FOR TRANSPLANTATIONR37DK037034 · NIDDK · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI LEMASTERS, JOHN J · 1998 to 2007
$4.0M
LIVER PRESERVATION FOR TRANSPLANTATIONR01DK037034 · NIDDK · UNIVERSITY OF NORTH CAROLINA CHAPEL HILL · PI LEMASTERS, JOHN J · 1986 to 2012
$3.1M
Mechanisms of I/R Injury to HepatocytesR01DK073336 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LEMASTERS, JOHN J · 2007 to 2017
$2.5M
MUSC FACIL EXPANSION &RENOV: SLE C06RR015455 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI RAYMOND, JOHN R · 2002 to 2002
$2.0M
Transplantation of Reduced-Size Fatty LiversR01DK070844 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI ZHONG, ZHI · 2006 to 2010
$1.3M
Confocal/Multiphoton Microscope UpgradeS10OD018113 · OD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LEMASTERS, JOHN J · 2015 to 2015
$570k
Liver Preservation for TransplantationR56DK037034 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI LEMASTERS, JOHN J · 2014 to 2014
$282k
NCI NIH HHS P30 CA138313NCRR NIH HHS C06 RR015455NIDDK NIH HHS R01 DK037034NIDDK NIH HHS R01 DK070844NIDDK NIH HHS R01 DK073336NIDDK NIH HHS R37 DK037034NIDDK NIH HHS R56 DK037034NIH HHS S10 OD018113
6 · The paper itself

Abstract

Permeant cGMP analogs prevent the mitochondria permeability transition (MPT)

Indexed as

Cyclic GMPfatty liverliver regenerationmitochondrial permeability transitionpartial liver graftsteatosis

Identifiers

PMID28694919
PMCPMC5498880
OpenAlexW2991557701

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.