ArticleOxidative medicine and cellular longevity2017
Heme Oxygenase-1, a Key Enzyme for the Cytoprotective Actions of Halophenols by Upregulating Nrf2 Expression via Activating Erk1/2 and PI3K/Akt in EA.hy926 Cells.
Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- A microbial metabolite reduces alcohol-induced inflammation via dual modulation of NF-κB and Interferon pathway.bioRxiv : the preprint server for biology · 2026Article
- ERK1/2 activation in anti-inflammatory effects and underlying signaling mechanisms.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Review
- Hemin as a protective agent in an in vitro model of hypoxia/reoxygenation-induced injury.SAGE open medicine · 2025Article
- Baicalin improves isoproterenol-induced cardiac remodeling by regulating the Nrf2-dependent signaling pathway.BMC cardiovascular disorders · 2024Article
- Genetic and histopathological analysis of spermatogenesis after short-term testicular torsion in rats.Pediatric research · 2023Article
- Insights on the role of L-lactate as a signaling molecule in skin aging.Biogerontology · 2023Review
- Toxic consequences and oxidative protein carbonylation from chloropicrin exposure in human corneal epithelial cells.Toxicology letters · 2020Article
- Process Development and Synthesis of Process-Related Impurities of an Efficient Scale-Up Preparation of 5,2'-Dibromo-2,4',5'-Trihydroxy Diphenylmethanone as a New Acute Pyelonephritis Candidate Drug.Molecules (Basel, Switzerland) · 2020Article
- Heme oxygenase 1 facilitates cell proliferation via the B-Raf-ERK signaling pathway in melanoma.Cell communication and signaling : CCS · 2019Article
- Keap1/Nrf2 Signaling: A New Player in Thyroid Pathophysiology and Thyroid Cancer.Frontiers in endocrinology · 2019Review
- 5,2'-dibromo-2,4',5'-trihydroxydiphenylmethanone attenuates LPS-induced inflammation and ROS production in EA.hy926 cells via HMBOX1 induction.Journal of cellular and molecular medicine · 2019Article
- Comparison of Antioxidative Effects of Insect Tea and Its Raw Tea (Kuding Tea) Polyphenols in Kunming Mice.Molecules (Basel, Switzerland) · 2018Article
- Synthesis of Novel Nitrogen-Containing Heterocycle Bromophenols and Their Interaction with Keap1 Protein by Molecular Docking.Molecules (Basel, Switzerland) · 2017Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Increasing evidence has demonstrated that heme oxygenase-1 (HO-1) is a key enzyme triggered by cellular stress, exhibiting cytoprotective, antioxidant, and anti-inflammatory abilities. Previously, we prepared a series of novel active halophenols possessing strong antioxidant activities in vitro and in vivo. In the present study, we demonstrated that these halophenols exhibited significant protective effects against H
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