Evidence map›Paper›PMID 28694897›Full record

ArticleWideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques2017

The effects of prolonged CO

Dogan Yildirim, Turgut Donmez, Oguzhan Sunamak, Semih Mirapoglu, Adnan Hut, Nilgun Rukiye Erdogan, Zumrut Mine Isık Saglam, Huseyin Kilincaslan

Open access · goldAbstract read
In one paragraph

Article in Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Dogan YildirimDepartment of General Surgery, Haseki Training and Research Hospital, Istanbul, Turkey.
Turgut DonmezDepartment of General Surgery, Lutfiye Nuri Burat State Hospital, Istanbul, Turkey.
Oguzhan SunamakDepartment of General Surgery, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.
Semih MirapogluDepartment of Pediatric Surgery, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.
Adnan HutDepartment of General Surgery, Haseki Training and Research Hospital, Istanbul, Turkey.
Nilgun Rukiye ErdoganDepartment of Pathology, Avrasya Hospital, Istanbul, Turkey.
Zumrut Mine Isık SaglamDepartment of Biochemistry, Haseki Training and Research Hospital, Istanbul, Turkey.
Huseyin KilincaslanDepartment of Pediatric Surgery, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.
Haseki Eğitim ve Araştırma Hastanesi · TRBezmiâlem Vakıf Üniversitesi · TRAvrasya University · TRHaydarpaşa Numune Eğitim ve Araştırma Hastanesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPneumoperitoneum (PP) is known to cause ischemia in kidneys and other intra-abdominal organs because of decreased splanchnic blood flow.

aimWe aimed to determine the degree of renal injury that occurs due to a PP and prolonged PP. We measured renal injury biomarkers and made a histopathological evaluation to estimate the degree of injury and assessed the correlation of biomarkers with histopathological findings. MATERIAL AND

methodsTwenty-one female Sprague Dawley rats were separated randomly into three groups. Group 1 was the control group and was given anesthesia for 3 h. In group 2, a PP was administered under anesthesia for 1 h. A pneumoperitoneum was administered under anesthesia to animals in group 3 for 3 h.

resultsPathological analysis showed a significant statistical difference between the 3 groups. In particular, neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C (Cys C) levels at the 24

conclusionsThe increase in NGAL and Cys C levels directly correlated with the duration of PP and intra-abdominal pressure, and they are therefore good biomarkers in diagnosing acute renal injury in the early phase. Serum creatinine level is not a good biomarker in the early phase of renal injury.

Indexed as

acute kidney injurycystatin Cneutrophil gelatinase-associated lipocalinpneumoperitoneumrats

Identifiers

PMID28694897
PMCPMC5502337
OpenAlexW2610002237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.