ReviewBeilstein journal of organic chemistry2017
Towards open-ended evolution in self-replicating molecular systems.
Review in Beilstein journal of organic chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Functional abiotic metabolite assembly hypothesis for the early events in the origin of life.Nature communications · 2026Review
- Article
- Covalent Dynamic DNA Networks to Translate Multiple Inputs into Programmable Outputs.Journal of the American Chemical Society · 2025Article
- Emergent Behavior of a Photoswitchable Solute in a Biphasic Solvent System.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024Article
- Template-based copying in chemically fuelled dynamic combinatorial libraries.Nature chemistry · 2024Article
- Could Life Have Started on Mars? Planetary Conditions That Assemble and Destroy Protocells.Life (Basel, Switzerland) · 2024Article
- Evolution at the Origins of Life?Life (Basel, Switzerland) · 2024Review
- The Long Road to a Synthetic Self-Replicating Central Dogma.Biochemistry · 2023Review
- Growth, replication and division enable evolution of coacervate protocells.Chemical communications (Cambridge, England) · 2022Review
- Out-of-Equilibrium Self-Replication Allows Selection for Dynamic Kinetic Stability in a System of Competing Replicators.Angewandte Chemie (International ed. in English) · 2022Article
- RNA World Modeling: A Comparison of Two Complementary Approaches.Entropy (Basel, Switzerland) · 2022Article
- An Optical Probe for Real-Time Monitoring of Self-Replicator Emergence and Distinguishing between Replicators.Journal of the American Chemical Society · 2022Article
- An Approach to the De Novo Synthesis of Life.Accounts of chemical research · 2022Article
- Molecular basis of Arginine and Lysine DNA sequence-dependent thermo-stability modulation.PLoS computational biology · 2022Article
- Chemical engines: driving systems away from equilibrium through catalyst reaction cycles.Nature nanotechnology · 2021Review
- Selection between Competing Self-Reproducing Lipids: Succession and Dynamic Activation.JACS Au · 2021Article
- Chemical Fueling Enables Molecular Complexification of Self-Replicators*.Angewandte Chemie (International ed. in English) · 2021Article
- Parasitic behavior in competing chemically fueled reaction cycles.Chemical science · 2021Article
- Self-Reproduction and Darwinian Evolution in Autocatalytic Chemical Reaction Systems.Life (Basel, Switzerland) · 2021Review
- Toward Molecular Cooperation by De Novo Peptides.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this review we discuss systems of self-replicating molecules in the context of the origin of life and the synthesis of de novo life. One of the important aspects of life is the ability to reproduce and evolve continuously. In this review we consider some of the prerequisites for obtaining unbounded evolution of self-replicating molecules and describe some recent advances in this field. While evolution experiments involving self-replicating molecules have shown promising results, true open-ended evolution has not been realized so far. A full understanding of the requirements for open-ended evolution would provide a better understanding of how life could have emerged from molecular building blocks and what is needed to create a minimal form of life in the laboratory.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.