ArticleFrontiers in zoology2017
Gene expression profiling of whole blood cells supports a more efficient mitochondrial respiration in hypoxia-challenged gilthead sea bream (
Article in Frontiers in zoology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- Effects of acute cold stress on the physiological and biochemical dynamics of Nile tilapia (Oreochromis niloticus Linn.): in vivo and in vitro studies.Fish physiology and biochemistry · 2026Article
- Effect of Functional Electrical Stimulation Combined With Physical Exercise on Electron Transport Chain Activity in Peripheral Blood Cells of Stroke Patients.Artificial organs · 2025Article
- Feeding for Well-Being: Porcine Blood Hydrolysate Supplementation Improves Metabolic and Welfare-Related Traits in Farmed Gilthead Sea Bream (International journal of molecular sciences · 2025Article
- Comparative Transcriptomic Analysis for Identification of Environmental-Responsive Genes in Seven Species of Threadfin Breams (International journal of molecular sciences · 2025Article
- Article
- The effect of environmental stressors on growth in fish and its endocrine control.Frontiers in endocrinology · 2023Review
- Canine urinary lactate and cortisol metabolites in hypercortisolism, nonadrenal disease, congestive heart failure, and health.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022Article
- Effect of Artificial Regime Shifts and Biotic Factors on the Intensity of Foraging of Planktivorous Fish.Animals : an open access journal from MDPI · 2021Article
- Convergent evolution of a genomic rearrangement may explain cancer resistance in hystrico- and sciuromorpha rodents.NPJ aging and mechanisms of disease · 2021Article
- Transcriptomic profiling of Gh/Igf system reveals a prompted tissue-specific differentiation and novel hypoxia responsive genes in gilthead sea bream.Scientific reports · 2021Article
- Diet and Exercise Modulate GH-IGFs Axis, Proteolytic Markers and Myogenic Regulatory Factors in Juveniles of Gilthead Sea Bream (Animals : an open access journal from MDPI · 2021Article
- Targeting the Mild-Hypoxia Driving Force for Metabolic and Muscle Transcriptional Reprogramming of Gilthead Sea Bream (Biology · 2021Article
- Effects of genetics and early-life mild hypoxia on size variation in farmed gilthead sea bream (Sparus aurata).Fish physiology and biochemistry · 2021Article
- Blood Will Tell: What Hematological Analyses Can Reveal About Fish Welfare.Frontiers in veterinary science · 2021Review
- Article
- Acute hypoxia/reoxygenation affects muscle mitochondrial respiration and redox state as well as swimming endurance in zebrafish.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2019Article
- Ultra-Low Power Sensor Devices for Monitoring Physical Activity and Respiratory Frequency in Farmed Fish.Frontiers in physiology · 2019Article
- Tissue-Specific Orchestration of Gilthead Sea Bream Resilience to Hypoxia and High Stocking Density.Frontiers in physiology · 2019Article
- Somatotropic Axis Regulation Unravels the Differential Effects of Nutritional and Environmental Factors in Growth Performance of Marine Farmed Fishes.Frontiers in endocrinology · 2018Review
- Co-expression Analysis of Sirtuins and Related Metabolic Biomarkers in Juveniles of Gilthead Sea Bream (Frontiers in physiology · 2018Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcclimation to abiotic challenges, including decreases in O
methodsJuvenile gilthead sea bream (
resultsBlood physiological hallmarks remained almost unaltered at 3.0 ppm, but the haematocrit and circulating levels of haemoglobin, glucose and lactate were consistently increased when fish were maintained below the limiting oxygen saturation at 1.3 ppm. These findings were concurrent with an increase in total plasma antioxidant activity and plasma cortisol levels, whereas the opposite trend was observed for growth-promoting factors, such as insulin-like growth factor I. Additionally, gene expression profiling of whole blood cells revealed changes in upstream master regulators of mitochondria (
conclusionsOur results demonstrate the re-adjustment of mitochondrial machinery at transcriptional level to cope with a decreased basal metabolic rate, consistent with a low risk of oxidative stress, diminished aerobic ATP production and higher O
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.