ReviewFrontiers in pharmacology2017
Pharmacological Properties and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical Development.
Review in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05427721 (Thymol Administration Effects on Netrin-1 Serum Concentration on Obese Patients), which is not on this map. Cited by 214 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Thymol Administration Effects on Netrin-1 Serum Concentration on Obese Patients
Who cites it
214 citing papers in PubMed, 3 syntheses or guidelines pooled it, 559 citations in OpenAlex.
- Cold pressed oils: a systematic review on physicochemical properties, nutritional composition and pharmacological activities.Frontiers in nutrition · 2026Pooled it
- The therapeutic potential of terpenes in periodontal disease: a systematic review of pre-clinical animal studies.Inflammopharmacology · 2025Pooled it
- Pharmaco-toxicological aspects of thymol in veterinary medicine. A systematic review.Frontiers in veterinary science · 2025Pooled it
- Effects of Satureja Khuzestanica supplementation on glycemic indices and lipid profile in type 2 diabetes patients: a randomized controlled clinical-trial.BMC complementary medicine and therapies · 2024Trial
- Antibacterial, Anti-Inflammatory and Anti-Melanogenic Effects of a Novel Peptide.Annals of dermatology · 2026Article
- Investigating the effects of thymol and cinnamaldehyde in T-2 toxin-treated hepatic cell cultures of chicken origin.Poultry science · 2026Article
- Protective Effect of a Polyherbal Formulation (Cardojith) Against Angiotensin II-induced Hypertension and Cardiomyocyte Hypertrophy Via Modulation of Oxidative Stress and MAPK Signalling.Applied biochemistry and biotechnology · 2026Article
- Biological and Phytochemical Profile of Volatile Oils from Romanian Mountain Flora.Pharmaceuticals (Basel, Switzerland) · 2026Article
- Developmental Dynamics of Bioactive Compound Accumulation During Vegetative Growth in Thymus daenensis Čelak.Chemistry & biodiversity · 2026Article
- Stage-Specific Insecticidal Activity of Thymol Against Colorado Potato Beetle and Time-Dependent Detoxification Gene Expression.Chemistry & biodiversity · 2026Article
- Computational insight into the antioxidant activity of thymol in diverse solvent environments: a DFT approach.Journal of molecular modeling · 2026Article
- Ecotoxicity evaluation of thymol in tunneller dung beetles (Coleoptera: Geotrupidae) as a natural alternative to ecotoxic anthelmintics.Ecotoxicology (London, England) · 2026Article
- Pistacia atlantica subsp. mutica essencial oil enhances proliferation and telomerase activity in senescent mesenchymal stem cells.BMC complementary medicine and therapies · 2026Article
- Thymol modulates rumen barrier function and inflammation in feed-restricted lambs.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Spices Beyond Antioxidants: From the Gut to the Brain.Nutrition reviews · 2026Review
- Antibacterial Packaging for Cheese Based on Carboxymethyl Cellulose Composite with Zinc Oxide and Thyme Essential Oil.Foods (Basel, Switzerland) · 2026Article
- Sustainable Applications of Thymol: Advances in Formulation Technologies, Drug Delivery Systems, and Food Preservation Strategies.Food science & nutrition · 2026Review
- Phytogenic feed additive mitigates necrotic enteritis-associated gut damage and performance loss in broilers.Poultry science · 2026Article
- Biological activities (antimicrobial, anti-inflammatory, anti-coronavirus (229E)) and chemical composition of some essential oils.Scientific reports · 2026Article
- Comparison of the antimicrobial, anti-biofilm, and cytotoxic effects of thymol/ampicillin and thymol/cefotaxime against Escherichia coli bacteria.BMC research notes · 2026Article
154 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thymol, chemically known as 2-isopropyl-5-methylphenol is a colorless crystalline monoterpene phenol. It is one of the most important dietary constituents in thyme species. For centuries, it has been used in traditional medicine and has been shown to possess various pharmacological properties including antioxidant, free radical scavenging, anti-inflammatory, analgesic, antispasmodic, antibacterial, antifungal, antiseptic and antitumor activities. The present article presents a detailed review of the scientific literature which reveals the pharmacological properties of thymol and its multiple therapeutic actions against various cardiovascular, neurological, rheumatological, gastrointestinal, metabolic and malignant diseases at both biochemical and molecular levels. The noteworthy effects of thymol are largely attributed to its anti-inflammatory (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.