Evidence map›Paper›PMID 28694699›Full record

ArticleInternational journal of nanomedicine2017

Antitumor HPV E7-specific CTL activity elicited by in vivo engineered exosomes produced through DNA inoculation.

Paola Di Bonito, Chiara Chiozzini, Claudia Arenaccio, Simona Anticoli, Francesco Manfredi, Eleonora Olivetta, Flavia Ferrantelli, Emiliana Falcone, Anna Ruggieri, Maurizio Federico

Open access · goldAbstract read
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 74 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Engineered exosomes from different sources for cancer-targeted therapy.Signal transduction and targeted therapy · 2023
    Review
  8. Extracellular Vesicles and Viruses: Two Intertwined Entities.International journal of molecular sciences · 2023
    Review
  9. Organism-Generated Biological Vesicles In Situ: An Emerging Drug Delivery Strategy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Extracellular Vesicles and Their Use as Vehicles of Immunogens.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  15. Small extracellular vesicles in cancer.Bioactive materials · 2021
    Review
  16. Review
  17. Virus-Induced CD8Vaccines · 2021
    Article
  18. Review
  19. Emerging Role of Nef in the Development of HIV Associated Neurological Disorders.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Paola Di BonitoDepartment of Infectious, Parasitic and Immunomediated Diseases, Istituto Superiore di Sanità, Rome, Italy.
Chiara ChiozziniNational AIDS Center, Istituto Superiore di Sanità, Rome, Italy.
Claudia ArenaccioNational AIDS Center, Istituto Superiore di Sanità, Rome, Italy.
Simona AnticoliNational AIDS Center, Istituto Superiore di Sanità, Rome, Italy.
Francesco ManfrediNational AIDS Center, Istituto Superiore di Sanità, Rome, Italy.
Eleonora OlivettaNational AIDS Center, Istituto Superiore di Sanità, Rome, Italy.
Flavia FerrantelliNational AIDS Center, Istituto Superiore di Sanità, Rome, Italy.
Emiliana FalconeDepartment of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Rome, Italy.
Anna RuggieriDepartment of Veterinary Public Health and Food Safety, Istituto Superiore di Sanità, Rome, Italy.
Maurizio FedericoNational AIDS Center, Istituto Superiore di Sanità, Rome, Italy.
Istituto Superiore di Sanità · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We recently proved that exosomes engineered in vitro to deliver high amounts of HPV E7 upon fusion with the Nef

Indexed as

AnimalsAntigensAntineoplastic AgentsCD8-Positive T-LymphocytesDNAExosomesFemaleGenes, nefGenetic EngineeringGenetic VectorsMice, Inbred C57BLPapillomavirus E7 ProteinsT-Lymphocytes, CytotoxicAntigensAntineoplastic AgentsDNAPapillomavirus E7 Proteinscytotoxic T lymphocytesDNA vectorsHIV-1 Nefnanovesicles

Identifiers

PMID28694699
PMCPMC5491702
OpenAlexW2629399988

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.