Evidence map›Paper›PMID 28694685›Full record

ArticleDrug design, development and therapy2017

Differential effect of platelet-rich plasma fractions on β1-integrin signaling, collagen biosynthesis, and prolidase activity in human skin fibroblasts.

Tomasz Guszczyn, Arkadiusz Surażyński, Ilona Zaręba, Edyta Rysiak, Janusz Popko, Jerzy Pałka

Open access · goldAbstract read
In one paragraph

Article in Drug design, development and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

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  13. Extracellular Prolidase (PEPD) Induces Anabolic Processes through EGFR, βInternational journal of molecular sciences · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tomasz GuszczynDepartment of Pediatric Orthopedics and Traumatology.
Arkadiusz SurażyńskiDepartment of Medicinal Chemistry, Medical University of Białystok, Białystok, Poland.
Ilona ZarębaDepartment of Medicinal Chemistry, Medical University of Białystok, Białystok, Poland.
Edyta RysiakDepartment of Medicinal Chemistry, Medical University of Białystok, Białystok, Poland.
Janusz PopkoDepartment of Pediatric Orthopedics and Traumatology.
Jerzy PałkaDepartment of Medicinal Chemistry, Medical University of Białystok, Białystok, Poland.
Medical University of Białystok · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study was conducted to evaluate the effects of platelet-rich plasma (PRP), supernatant of PRP (SPRP) obtained by centrifugation, and supernatant of activated PRP (SActi-PRP) obtained by Ca

Indexed as

Cells, CulturedCollagenDipeptidasesDNADose-Response Relationship, DrugFibroblastsFocal Adhesion Kinase 1HumansIntegrin beta1Mitogen-Activated Protein KinasesPlatelet-Rich PlasmaSignal TransductionSkinCollagenDipeptidasesDNAFocal Adhesion Kinase 1Integrin beta1Mitogen-Activated Protein Kinasesproline dipeptidaseFAKfibroblastsMAPK

Identifiers

PMID28694685
PMCPMC5491703
OpenAlexW2670450436

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.