ArticleThe Journal of manual & manipulative therapy2017
A clinical perspective on a pain neuroscience education approach to manual therapy.
Article in The Journal of manual & manipulative therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of Pain Neuroscience Education in Patients with Chronic Musculoskeletal Pain and Central Sensitization: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- Exploring the immediate and short-term effect of lumbar spinal manipulation on pressure pain threshold: a randomized controlled trial of healthy participants.Chiropractic & manual therapies · 2024Trial
- Effects of Manual Therapy Plus Pain Neuroscience Education with Integrated Motivational Interviewing in Individuals with Chronic Non-Specific Low Back Pain: A Randomized Clinical Trial Study.Medicina (Kaunas, Lithuania) · 2024Trial
- Immediate effect of pain neuroscience education for recent onset low back pain: an exploratory single arm trial.The Journal of manual & manipulative therapy · 2019Trial
- Article
- Assessment of pain neurophysiology knowledge among healthcare students in Bayero University Kano, Nigeria: a cross-sectional study.BMC medical education · 2026Article
- Use of pain neuroscience education, balance evaluation, and exercise for treating chronic pain with kinesiophobia: a narrative review with clinical recommendations.Frontiers in public health · 2026Review
- Pain Neuroscience Education Reduces Pain and Improves Psychological Variables but Does Not Induce Plastic Changes Measured by Brain-Derived Neurotrophic Factor (BDNF): A Randomized Double-Blind Clinical Trial.Healthcare (Basel, Switzerland) · 2025Article
- Effectiveness of Adding a Pain Neuroscience Education Program to a Multimodal Physiotherapy Intervention in Patients with Chronic Shoulder Pain: A Randomized Clinical Trial.Brain sciences · 2025Article
- From didactic explanations to co-design, sequential art and embodied learning: challenges, criticisms and future directions of patient pain education.Frontiers in pain research (Lausanne, Switzerland) · 2025Review
- "Hands-On" and "Hands-Off" Physiotherapy Treatments in Fibromyalgia Patients: A Systematic Review and Meta-Analysis.Biomedicines · 2024Review
- New clinical decision tool to assist physical therapists with joint mobilization application to the pediatric population.The Journal of manual & manipulative therapy · 2024Review
- A modern way to teach and practice manual therapy.Chiropractic & manual therapies · 2024Review
- Article
- A Manifesto in Defense of Pain Complexity: A Critical Review of Essential Insights in Pain Neuroscience.Journal of clinical medicine · 2023Review
- Review
- Carpal Tunnel Syndrome: Neuropathic Pain Associated or Not with a Nociplastic Condition.Biomedicines · 2023Article
- Myofascial Pain Syndrome: A Nociceptive Condition Comorbid with Neuropathic or Nociplastic Pain.Life (Basel, Switzerland) · 2023Article
- Letter to the Editor: Virtual McKenzie extension exercises for low back and leg pain: a prospective pilot exploratory case series. Journal of Manual and Manipulative Therapy, DOI:10.1080/10669817.2092822.The Journal of manual & manipulative therapy · 2023Article
- Yoga and pain: A mind-body complex system.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, there has been an increased interest in pain neuroscience education (PNE) in physical therapy. There is growing evidence for the efficacy of PNE to decrease pain, disability, fear-avoidance, pain catastrophization, limited movement, and health care utilization in people struggling with pain. PNE teaches people in pain more about the biology and physiology of their pain experience including processes such as central sensitization, peripheral sensitization, allodynia, inhibition, facilitation, neuroplasticity and more. PNE's neurobiological model often finds itself at odds with traditional biomedical models used in physical therapy. Traditional biomedical models, focusing on anatomy, pathoanatomy, and biomechanics have been shown to have limited efficacy in helping people understand their pain, especially chronic pain, and may in fact even increase a person's pain experience by increasing fear-avoidance and pain catastrophization. An area of physical therapy where the biomedical model is used a lot is manual therapy. This contrast between PNE and manual therapy has seemingly polarized followers from each approach to see PNE as a 'hands-off' approach even having clinicians categorize patients as either in need of receiving PNE (with no hands-on), or hands-on with no PNE. In this paper, we explore the notion of PNE and manual therapy co-existing. PNE research has shown to have immediate effects of various clinical signs and symptoms associated with central sensitization. Using a model of sensitization (innocuous, noxious, and allodynia), we argue that PNE can be used in a manual therapy model, especially treating someone where the nervous system has become increasingly hypervigilant.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.