Evidence map›Paper›PMID 28694672›Full record

ArticleWorld journal of gastroenterology2017

Benefit of everolimus in treatment of an intrahepatic cholangiocarcinoma patient with a

Ji-Lai Bian, Mei-Mei Wang, En-Juan Tong, Jing Sun, Ming Li, Zhi-Bo Miao, Yan-Lin Li, Bai-Hong Zhu, Jia-Jia Xu

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Case Report: FGFR2 inhibitor resistance viaFrontiers in oncology · 2025
    Article
  3. Review
  4. [The companion diagnostics of targeted therapy and immunotherapy for hepatocellular carcinoma].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2022
    Article
  5. Article
  6. Article
  7. Third-line sunitinib treatment in aCancer biology & therapy · 2020
    Review
  8. Article
  9. mTOR Inhibitors in Advanced Biliary Tract Cancers.International journal of molecular sciences · 2019
    Review
  10. Autophagy Modulation in Cancer: Current Knowledge on Action and Therapy.Oxidative medicine and cellular longevity · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Ji-Lai BianJi-Lai Bian, Mei-Mei Wang, En-Juan Tong, Jing Sun, Ming Li, Department of Medical Oncology, The Fifth People's Hospital of Dalian, Dalian 116021, Liaoning Province, China.
Mei-Mei WangJi-Lai Bian, Mei-Mei Wang, En-Juan Tong, Jing Sun, Ming Li, Department of Medical Oncology, The Fifth People's Hospital of Dalian, Dalian 116021, Liaoning Province, China.
En-Juan TongJi-Lai Bian, Mei-Mei Wang, En-Juan Tong, Jing Sun, Ming Li, Department of Medical Oncology, The Fifth People's Hospital of Dalian, Dalian 116021, Liaoning Province, China.
Jing SunJi-Lai Bian, Mei-Mei Wang, En-Juan Tong, Jing Sun, Ming Li, Department of Medical Oncology, The Fifth People's Hospital of Dalian, Dalian 116021, Liaoning Province, China.
Ming LiJi-Lai Bian, Mei-Mei Wang, En-Juan Tong, Jing Sun, Ming Li, Department of Medical Oncology, The Fifth People's Hospital of Dalian, Dalian 116021, Liaoning Province, China.
Zhi-Bo MiaoJi-Lai Bian, Mei-Mei Wang, En-Juan Tong, Jing Sun, Ming Li, Department of Medical Oncology, The Fifth People's Hospital of Dalian, Dalian 116021, Liaoning Province, China.
Yan-Lin LiJi-Lai Bian, Mei-Mei Wang, En-Juan Tong, Jing Sun, Ming Li, Department of Medical Oncology, The Fifth People's Hospital of Dalian, Dalian 116021, Liaoning Province, China.
Bai-Hong ZhuJi-Lai Bian, Mei-Mei Wang, En-Juan Tong, Jing Sun, Ming Li, Department of Medical Oncology, The Fifth People's Hospital of Dalian, Dalian 116021, Liaoning Province, China.
Jia-Jia XuJi-Lai Bian, Mei-Mei Wang, En-Juan Tong, Jing Sun, Ming Li, Department of Medical Oncology, The Fifth People's Hospital of Dalian, Dalian 116021, Liaoning Province, China.
The Third People's Hospital of Dalian City · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intrahepatic cholangiocarcinoma (ICC) is a relatively rare form of liver cancer with a poor prognosis. The therapeutic options for patients with advanced ICC are limited and usually ineffective. There is currently no approved targeted therapy for ICC, although accumulating evidence supports inhibition of the PI3K/Akt/mTOR signaling pathway as a promising therapeutic strategy in the treatment of ICC. Here, we report a patient with stage IV ICC harboring a

Indexed as

MutationAdultBile Duct NeoplasmsBile Ducts, IntrahepaticCholangiocarcinomaClass I Phosphatidylinositol 3-KinasesEverolimusGenomicsHigh-Throughput Nucleotide SequencingHumansImmunosuppressive AgentsMagnetic Resonance ImagingMalePrognosisTomography, X-Ray ComputedTreatment OutcomeClass I Phosphatidylinositol 3-KinasesEverolimusImmunosuppressive AgentsPIK3CA protein, humanEverolimusIntrahepatic cholangiocarcinomaNext generation sequencingPIK3CA

Identifiers

PMID28694672
PMCPMC5483506
OpenAlexW2702502510

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.