ArticleScientific reports2017
Ticks infected via co-feeding transmission can transmit Lyme borreliosis to vertebrate hosts.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 54 citations in OpenAlex.
- Emergence, global dispersal, and local adaptations ofApplied and environmental microbiology · 2026Review
- Investigation of avian louse flies as potential vectors of protozoan and bacterial pathogens of veterinary importance.Scientific reports · 2025Article
- Rapid Northward Expansion of the Blacklegged Tick, Ixodes scapularis, in Response to Climate Change.Global change biology · 2025Article
- Abundance of ticks and tick-borne pathogens in domestic gardens in Belgium, 2020-2022: a citizen science approach.BMC public health · 2025Article
- Tick phenology, tick-host associations, and tick-borne pathogen surveillance in a recreational forest of East Texas, USA.PloS one · 2025Article
- Adaptive immunity inApplied and environmental microbiology · 2024Article
- Development, Optimization, and Validation of a Quantitative PCR Assay forPathogens (Basel, Switzerland) · 2024Article
- Seasonal infestation patterns of ticks on Hokkaido sika deer (Parasitology · 2024Article
- Molecular detection of some zoonotic tick-borne pathogens in ticks collected from camels (Camelus dromedarius) as hosts and wild rodents as potential reservoirs.Veterinary research communications · 2024Article
- Ticking off the Tick Vectors:Pathogens (Basel, Switzerland) · 2023Article
- Tick-to-host transmission differs betweenMicrobiology spectrum · 2023Article
- Deer management generally reduces densities of nymphal Ixodes scapularis, but not prevalence of infection with Borrelia burgdorferi sensu stricto.Ticks and tick-borne diseases · 2023Article
- A U.S. Isolate ofPathogens (Basel, Switzerland) · 2023Article
- Borrelia burgdorferi strain and host sex influence pathogen prevalence and abundance in the tissues of a laboratory rodent host.Molecular ecology · 2022Article
- Detection of Tick-Borne Pathogens in Ticks from Cattle in Western Highlands of Cameroon.Microorganisms · 2022Article
- Patterns of deer ked (Diptera: Hippoboscidae) and tick (Ixodida: Ixodidae) infestation on white-tailed deer (Odocoileus virginianus) in the eastern United States.Parasites & vectors · 2022Article
- What do we know about the microbiome ofFrontiers in cellular and infection microbiology · 2022Review
- Epizootiological aspects of natural nidality ofVeterinary world · 2022Article
- Borrelia afzelii Infection in the Rodent Host Has Dramatic Effects on the Bacterial Microbiome of Ixodes ricinus Ticks.Applied and environmental microbiology · 2021Article
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vector-borne pathogens establish systemic infections in host tissues to maximize transmission to arthropod vectors. Co-feeding transmission occurs when the pathogen is transferred between infected and naive vectors that feed in close spatiotemporal proximity on a host that has not yet developed a systemic infection. Borrelia afzelii is a tick-borne spirochete bacterium that causes Lyme borreliosis (LB) and is capable of co-feeding transmission. Whether ticks that acquire LB pathogens via co-feeding are actually infectious to vertebrate hosts has never been tested. We created nymphs that had been experimentally infected as larvae with B. afzelii via co-feeding or systemic transmission, and compared their performance over one complete LB life cycle. Co-feeding nymphs had a spirochete load that was 26 times lower than systemic nymphs but both nymphs were highly infectious to mice (i.e., probability of nymph-to-host transmission of B. afzelii was ~100%). The mode of transmission had no effect on the other infection phenotypes of the LB life cycle. Ticks that acquire B. afzelii via co-feeding transmission are highly infectious to rodents, and the resulting rodent infection is highly infectious to larval ticks. This is the first study to show that B. afzelii can use co-feeding transmission to complete its life cycle.
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