Evidence map›Paper›PMID 28694430›Full record

ArticleScientific reports2017

Map3k8 controls granulocyte colony-stimulating factor production and neutrophil precursor proliferation in lipopolysaccharide-induced emergency granulopoiesis.

Ángela Sánchez, Carlos Relaño, Araceli Carrasco, Constanza Contreras-Jurado, Antonio Martín-Duce, Ana Aranda, Susana Alemany

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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  11. Neutrophil Maturity in Cancer.Frontiers in immunology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ángela SánchezInstituto de Investigaciones Biomédicas "Alberto Sols" Madrid, Consejo Superior de Investigaciones Científicas (CSIC-UAM), Madrid, Spain.
Carlos RelañoInstituto de Investigaciones Biomédicas "Alberto Sols" Madrid, Consejo Superior de Investigaciones Científicas (CSIC-UAM), Madrid, Spain.
Araceli CarrascoInstituto de Investigaciones Biomédicas "Alberto Sols" Madrid, Consejo Superior de Investigaciones Científicas (CSIC-UAM), Madrid, Spain.
Constanza Contreras-JuradoInstituto de Investigaciones Biomédicas "Alberto Sols" Madrid, Consejo Superior de Investigaciones Científicas (CSIC-UAM), Madrid, Spain.
Antonio Martín-DuceInstituto de Investigaciones Biomédicas "Alberto Sols" Madrid, Consejo Superior de Investigaciones Científicas (CSIC-UAM), Madrid, Spain.
Ana ArandaInstituto de Investigaciones Biomédicas "Alberto Sols" Madrid, Consejo Superior de Investigaciones Científicas (CSIC-UAM), Madrid, Spain.
Susana AlemanyInstituto de Investigaciones Biomédicas "Alberto Sols" Madrid, Consejo Superior de Investigaciones Científicas (CSIC-UAM), Madrid, Spain. salemany@iib.uam.es.
Instituto de Investigaciones Biomédicas Sols-Morreale · ESConsejo Superior de Investigaciones Científicas · ESUniversidad de Las Palmas de Gran Canaria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Map3k8 has been proposed as a useful target for the treatment of inflammatory diseases. We show here that during lipopolysaccharide-induced emergency granulopoiesis, Map3k8 deficiency strongly impairs the increase in circulating mature (Ly6G

Indexed as

AnimalsAntigens, LyBone Marrow TransplantationCCAAT-Enhancer-Binding Protein-betaCD11b AntigenCell DifferentiationCell ProliferationCells, CulturedGranulocyte Colony-Stimulating FactorGranulocytesHematopoiesisLipopolysaccharidesMAP Kinase Kinase KinasesMiceNeutrophilsProto-Oncogene ProteinsAntigens, LyCCAAT-Enhancer-Binding Protein-betaCD11b AntigenCebpb protein, mouseGranulocyte Colony-Stimulating FactorLipopolysaccharidesLy6G antigen, mouseMap3k8 protein, mouseMAP Kinase Kinase KinasesProto-Oncogene Proteins

Identifiers

PMID28694430
PMCPMC5503936
OpenAlexW2726062659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.