Evidence map›Paper›PMID 28694328›Full record

ArticleRNA (New York, N.Y.)2017

The contribution of the C5 protein subunit of

Courtney N Niland, David R Anderson, Eckhard Jankowsky, Michael E Harris

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Multifunctional Hydroxyapatite Coated withMolecules (Basel, Switzerland) · 2020
    Article
  8. Approaches for measuring the dynamics of RNA-protein interactions.Wiley interdisciplinary reviews. RNA · 2020
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Courtney N NilandDepartment of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
David R AndersonZicklin School of Business, Baruch College, CUNY, New York, New York 10010, USA.
Eckhard JankowskyCenter for RNA Molecular Biology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
Michael E HarrisDepartment of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
University School · USBaruch College · US

Funding

GRADUATE TRAINING IN CELLULAR AND MOLECULAR BIOLOGYT32GM008056 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI DIEHL, JOHN ALAN, SNIDER, MARTIN D · 1985 to 2019
$7.1M
STRUCTURE/FUNCTION OF RIBONUCLEASE PR01GM056740 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI HARRIS, MICHAEL E. · 1998 to 2015
$4.8M
Mechanistic Enzymology of Phosphoryl Transfer EnzymesR01GM096000 · NIGMS · UNIVERSITY OF FLORIDA · PI HARRIS, MICHAEL E. · 2011 to 2017
$1.9M
NIGMS NIH HHS R01 GM056740NIGMS NIH HHS R01 GM096000NIGMS NIH HHS T32 GM008056
6 · The paper itself

Abstract

Recognition of RNA by RNA processing enzymes and RNA binding proteins often involves cooperation between multiple subunits. However, the interdependent contributions of RNA and protein subunits to molecular recognition by ribonucleoproteins are relatively unexplored. RNase P is an endonuclease that removes 5' leaders from precursor tRNAs and functions in bacteria as a dimer formed by a catalytic RNA subunit (P RNA) and a protein subunit (C5 in

Indexed as

Escherichia coli ProteinsNucleotidesRibonuclease PRNA PrecursorsRNA, TransferRNA, Transfer, MetSubstrate SpecificityEscherichia coli ProteinsNucleotidesRibonuclease Pribonuclease P, E coliRNA PrecursorsRNA, TransferRNA, Transfer, Metenzyme specificityhigh-throughput sequencingkineticsmolecular recognitionpre-tRNA processingRNase P

Identifiers

PMID28694328
PMCPMC5602109
OpenAlexW2736087247

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.