Evidence map›Paper›PMID 28694298›Full record

ArticleJournal of lipid research2017

Compound-specific isotope analysis resolves the dietary origin of docosahexaenoic acid in the mouse brain.

R J Scott Lacombe, Vanessa Giuliano, Stefanie M Colombo, Michael T Arts, Richard P Bazinet

Open access · hybridAbstract read
In one paragraph

Article in Journal of lipid research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 41 citations in OpenAlex.

  1. Trial
  2. Article
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  4. Review
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  7. Article
  8. Stable isotopes of fatty acids: current and future perspectives for advancing trophic ecology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020
    Review
  9. Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

R J Scott LacombeDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 3E2, Canada.
Vanessa GiulianoDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 3E2, Canada.
Stefanie M ColomboDepartment of Chemistry and Biology, Ryerson University, Toronto, Ontario M5B 2K3, Canada.
Michael T ArtsDepartment of Chemistry and Biology, Ryerson University, Toronto, Ontario M5B 2K3, Canada.
Richard P BazinetDepartment of Nutritional Sciences, Faculty of Medicine, University of Toronto, Toronto, Ontario M5S 3E2, Canada richard.bazinet@utoronto.ca.
University of Toronto · CAToronto Metropolitan University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DHA (22:6n-3) may be derived from two dietary sources, preformed dietary DHA or through synthesis from α-linolenic acid (ALA; 18:3n-3). However, conventional methods cannot distinguish between DHA derived from either source without the use of costly labeled tracers. In the present study, we demonstrate the proof-of-concept that compound-specific isotope analysis (CSIA) by GC-isotope ratio mass spectrometry (IRMS) can differentiate between sources of brain DHA based on differences in natural

Indexed as

AnimalsBrainDietary FatsDocosahexaenoic AcidsFemaleIsotopesMaleMethylationMiceMice, Inbred BALB CPregnancyDietary FatsDocosahexaenoic AcidsIsotopesfatty acidomega-3 fatty acidsstable isotope analysis

Identifiers

PMID28694298
PMCPMC5625118
OpenAlexW2734927163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.