Evidence map›Paper›PMID 28694291›Full record

ArticleInfection and immunity2017

Differential Regulation of Mas-Related G Protein-Coupled Receptor X2-Mediated Mast Cell Degranulation by Antimicrobial Host Defense Peptides and Porphyromonas gingivalis Lipopolysaccharide.

Kshitij Gupta, Chizobam Idahosa, Saptarshi Roy, Donguk Lee, Hariharan Subramanian, Anuradha Dhingra, Kathleen Boesze-Battaglia, Jonathan Korostoff, Hydar Ali

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Inflammatory Cells in Atherosclerosis.Antioxidants (Basel, Switzerland) · 2022
    Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Superantigenic Activation of Human Cardiac Mast Cells.International journal of molecular sciences · 2019
    Article
  12. Article
  13. Article
  14. Angiogenic Host Defense Peptide AG-30/5C and Bradykinin BJournal of immunology (Baltimore, Md. : 1950) · 2019
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kshitij GuptaDepartment of Pathology, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Chizobam IdahosaDepartment of Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Saptarshi RoyDepartment of Pathology, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Donguk LeeDepartment of Pathology, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Hariharan SubramanianDepartment of Pathology, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Anuradha DhingraDepartment of Biochemistry, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Kathleen Boesze-BattagliaDepartment of Biochemistry, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Jonathan KorostoffDepartment of Periodontics, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Hydar AliDepartment of Pathology, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA alih@upenn.edu.
University of Pennsylvania · US

Funding

Role of a novel human mast cell G protein coupled receptor in Allergy and InflammationR01AI124182 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Hydar Ali · 2016 to 2026
$2.5M
Lysosomal maturation during periodontal infectionsR01DE022465 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI BOESZE-BATTAGLIA, KATHLEEN · 2012 to 2016
$2.0M
A novel role for the adapter molecule NHERF1 in regulating asthma and allergic reR00HL121073 · NHLBI · MICHIGAN STATE UNIVERSITY · PI SUBRAMANIAN, HARIHARAN · 2016 to 2018
$734k
Human mast cell-specific Mas-related Gene-X2 (MrgX2) in Anaphylaxis and AsthmaR21AI108585 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI ALI, HYDAR · 2014 to 2015
$440k
A novel role for the adapter molecule NHERF1 in regulating asthma and allergic reK99HL121073 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI SUBRAMANIAN, HARIHARAN · 2014 to 2015
$216k
NHLBI NIH HHS K99 HL121073NHLBI NIH HHS R00 HL121073NIAID NIH HHS R01 AI124182NIAID NIH HHS R21 AI108585NIDCR NIH HHS R01 DE022465
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell DegranulationAntimicrobial Cationic PeptidesBacteroidaceae Infectionsbeta-DefensinsCathelicidinsCell LineChronic PeriodontitisFluorescent Antibody TechniqueGingivaHumansLipopolysaccharidesMast CellsNerve Tissue ProteinsPorphyromonas gingivalisReceptors, G-Protein-CoupledReceptors, NeuropeptideAntimicrobial Cationic Peptidesbeta-DefensinsCathelicidinsDEFB103A protein, humanLipopolysaccharidesMRGPRX2 protein, humanNerve Tissue ProteinsReceptors, G-Protein-CoupledReceptors, Neuropeptideantimicrobial peptideshost responselipopolysaccharidemast cellperiodontal immunologyPorphyromonas gingivalis

Identifiers

PMID28694291
PMCPMC5607414
OpenAlexW2734999506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.