ArticleBMC veterinary research2017
Goats as sentinel hosts for the detection of tick-borne encephalitis risk areas in the Canton of Valais, Switzerland.
Article in BMC veterinary research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 41 citations in OpenAlex.
- Identification and mapping of potential and highly likely vectors for selected vector-borne diseases in the EU and neighbouring countries.EFSA journal. European Food Safety Authority · 2026Article
- Tracking WNV transmission with a combined dog and wild boar surveillance system.Scientific reports · 2025Article
- Exposure of cattle to tick-borne encephalitis virus in the historical endemic zone in north-eastern France.BMC veterinary research · 2024Article
- An Overview of Tick-Borne Encephalitis Epidemiology in Endemic Regions of Continental Croatia, 2017-2023.Microorganisms · 2024Article
- Article
- Use of Wild Ungulates as Sentinels of TBEV Circulation in a Naïve Area of the Northwestern Alps, Italy.Life (Basel, Switzerland) · 2022Article
- Neurological disease suspected to be caused by tick-borne encephalitis virus infection in 6 horses in Switzerland.Journal of veterinary internal medicine · 2022Article
- Article
- Food-Borne Transmission of Tick-Borne Encephalitis Virus-Spread, Consequences, and Prophylaxis.International journal of environmental research and public health · 2022Review
- Article
- Increasing awareness for tick-borne encephalitis virus using small ruminants as suitable sentinels: Preliminary observations.One health (Amsterdam, Netherlands) · 2021Article
- Comparison of Three Serological Methods for the Epidemiological Investigation of TBE in Dogs.Microorganisms · 2021Article
- Presence of antibodies against tick-borne encephalitis virus in sheep in Tunisia, North Africa.BMC veterinary research · 2020Article
- Revealing new tick-borne encephalitis virus foci by screening antibodies in sheep milk.Parasites & vectors · 2020Article
- Tick-borne encephalitis foci in northeast Italy revealed by combined virus detection in ticks, serosurvey on goats and human cases.Emerging microbes & infections · 2020Article
- Potential Hazards Associated with Raw Donkey Milk Consumption: A Review.International journal of food science · 2019Review
- Equine viral encephalitis: prevalence, impact, and management strategies.Veterinary medicine (Auckland, N.Z.) · 2019Article
- The Role of Mammalian Reservoir Hosts in Tick-Borne Flavivirus Biology.Frontiers in cellular and infection microbiology · 2018Review
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTick-borne encephalitis (TBE) is an important tick-borne disease in Europe. Detection of the TBE virus (TBEV) in local populations of Ixodes ricinus ticks is the most reliable proof that a given area is at risk for TBE, but this approach is time-consuming and expensive. A cheaper and simpler approach is to use immunology-based methods to screen vertebrate hosts for TBEV-specific antibodies and subsequently test the tick populations at locations with seropositive animals.
resultsThe purpose of the present study was to use goats as sentinel animals to identify new risk areas for TBE in the canton of Valais in Switzerland. A total of 4114 individual goat sera were screened for TBEV-specific antibodies using immunological methods. According to our ELISA assay, 175 goat sera reacted strongly with TBEV antigen, resulting in a seroprevalence rate of 4.3%. The serum neutralization test confirmed that 70 of the 173 ELISA-positive sera had neutralizing antibodies against TBEV. Most of the 26 seropositive goat flocks were detected in the known risk areas in the canton of Valais, with some spread into the connecting valley of Saas and to the east of the town of Brig. One seropositive site was 60 km to the west of the known TBEV-endemic area. At two of the three locations where goats were seropositive, the local tick populations also tested positive for TBEV.
conclusionThe combined approach of screening vertebrate hosts for TBEV-specific antibodies followed by testing the local tick population for TBEV allowed us to detect two new TBEV foci in the canton of Valais. The present study showed that goats are useful sentinel animals for the detection of new TBEV risk areas.
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