Evidence map›Paper›PMID 28693505›Full record

SynthesisWorld journal of surgical oncology2017

Effects of radiofrequency ablation versus other ablating techniques on hepatocellular carcinomas: a systematic review and meta-analysis.

Wen Luo, Yunfei Zhang, Guangbin He, Ming Yu, Minjuan Zheng, Liwen Liu, Xiaodong Zhou

Abstract readComparative StudyMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in World journal of surgical oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  19. [Guidelines for image-guided ablation of primary liver cancer (2023 version)].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wen LuoDepartment of Ultrasound, Xijing Hospital, Fourth Military Medical University, No. 127 Changle Xi Road, Xi'an, China.
Yunfei ZhangResearch Institution of Bone tumor, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Guangbin HeDepartment of Ultrasound, Xijing Hospital, Fourth Military Medical University, No. 127 Changle Xi Road, Xi'an, China.
Ming YuDepartment of Ultrasound, Xijing Hospital, Fourth Military Medical University, No. 127 Changle Xi Road, Xi'an, China.
Minjuan ZhengDepartment of Ultrasound, Xijing Hospital, Fourth Military Medical University, No. 127 Changle Xi Road, Xi'an, China.
Liwen LiuDepartment of Ultrasound, Xijing Hospital, Fourth Military Medical University, No. 127 Changle Xi Road, Xi'an, China. zxdlwdd@163.com.
Xiaodong ZhouDepartment of Ultrasound, Xijing Hospital, Fourth Military Medical University, No. 127 Changle Xi Road, Xi'an, China. zxdlwdd@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPercutaneous ablation has quickly arisen as one of the important alternative treatments for hepatocellular carcinoma (HCC). We aimed to compare the therapeutic effects of radiofrequency ablation (RFA) and other ablative techniques on HCCs.

methodsDatabases were searched to identify literature on complete tumor ablation (CTA), overall survival (OS), local tumor recurrence (LTR), and complications of RFA in the treatment of HCC, compared with those of microwave ablation (MWA), percutaneous ethanol injection (PEI), PEI plus RFA, cryoablation (CRA), laser ablation (LSA), and high-intensity focused ultrasound. Randomized controlled trials and high-quality cohort studies were included in the assessment.

resultsThe effects of MWA and CRA appeared to be similar to those of RFA, but lower rates of LTR and higher rates of CTA in large tumors compared with RFA were reported (P < 0.05). CTA rates were lower in patients treated with PEI (odds ratio [OR] 0.16, 95% confidence interval [CI] 0.06-0.42), and higher in those treated with PEI plus RFA (OR 2.28, 95% CI 1.19-3.60), with an increased incidence of fever (P < 0.05). LSA resulted in lower CTA rates (OR 0.32, 95% CI 0.13-0.81) and OS (hazard ratio 1.47, 95% CI 1.01-2.15), with a lower incidence of complications.

conclusionsCompared with RFA, identical effects were found in MWA and CRA groups. Fewer complications were observed in PEI and LSA group. PEI plus RFA appeared more effective, with a higher rate of complications. Well-designed randomized controlled trials are further needed to confirm above results.

Indexed as

Carcinoma, HepatocellularCatheter AblationCryosurgeryHumansLiver NeoplasmsPrognosisAblative techniquesHepatocellular carcinomaRadiofrequency ablationTherapeutic effects

Identifiers

PMID28693505
PMCPMC5504820

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.