ArticleBMC infectious diseases2017
Inducible clindamycin and methicillin resistant Staphylococcus aureus in a tertiary care hospital, Kathmandu, Nepal.
Article in BMC infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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35 citing papers in PubMed, 91 citations in OpenAlex.
- Detection and Genotypic Characterization of Clindamycin Resistance AmongScientifica · 2026Article
- Whole-genome sequencing of clinical methicillin-resistant Staphylococcus aureus isolates across hospitals in Mwanza, Tanzania.Access microbiology · 2026Article
- Prevalence of methicillin-resistantIJID regions · 2025Article
- Antimicrobials profiling, biofilm formation, and clonal lineage of methicillin-resistantHeliyon · 2025Article
- Nasal Carriage of Methicillin-ResistantInterdisciplinary perspectives on infectious diseases · 2025Article
- Clindamycin-resistant among Staphylococcus aureus: Investigation into phenotypic and genotypic profiles.PloS one · 2025Article
- Methicillin and inducible clindamycin resistance in clinicalFrontiers in microbiology · 2025Article
- Inducible clindamycin-resistant and biofilm formation in the Staphylococcus aureus isolated from healthcare worker's anterior nasal carriage.BMC research notes · 2024Article
- A Multicenter Experience of Inducible Clindamycin Resistance in Staphylococcus aureus Infection among 800 Egyptian Patients with or without Diabetes Mellitus.The American journal of tropical medicine and hygiene · 2023Article
- Prevalence, antimicrobial susceptibility pattern and multidrug resistance of methicillin-resistantBMJ open · 2023Observational
- Inhibition of Erythromycin and Erythromycin-Induced Resistance amongAntibiotics (Basel, Switzerland) · 2023Article
- Penicillin and Oxacillin Loaded on PEGylated-Graphene Oxide to Enhance the Activity of the Antibiotics against Methicillin-ResistantPharmaceutics · 2022Article
- Phenotypic detection of methicillin resistance, biofilm production, and inducible clindamycin resistance in Staphylococcus aureus clinical isolates in Kathmandu, Nepal.Tropical medicine and health · 2022Article
- EudragitBiomedicines · 2022Article
- High level of persister frequency in clinical staphylococcal isolates.BMC microbiology · 2022Article
- New update on molecular diversity of clinical Staphylococcus aureus isolates in Iran: antimicrobial resistance, adhesion and virulence factors, biofilm formation and SCCmec typing.Molecular biology reports · 2022Article
- Prevalence and Clindamycin Resistance Profile ofInterdisciplinary perspectives on infectious diseases · 2022Article
- Mupirocin-ResistantBioMed research international · 2022Article
- Inducible Clindamycin-ResistantInternational journal of microbiology · 2022Review
- Staphylococcus aureus with inducible clindamycin resistance and methicillin resistance in a tertiary hospital in Nepal.Tropical medicine and health · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStaphylococcus aureus, an important nosocomial pathogen, is frequently associated with infections in human. The management of the infections by it especially methicillin resistant ones is often difficult because methicillin resistant S. aureus is usually resistant to multiple antibiotics. Macrolide-lincosamide streptogramin B family of antibiotics is commonly used to treat such infections as an alternative to vancomycin.
methodsThis study was conducted over the period of one and half year from November 2013-April 2015 in Microbiology laboratory of Nepal Medical College and Teaching Hospital, Kathmandu, Nepal to find the incidence of different phenotypes of MLS
resultsOf the 270 clinical isolates of S. aureus, 25.1% (68/270) were MRSA. Erythromycin and clindamycin resistance was seen in 54.4% (147/270) and 41.8% (113/270) isolates respectively. Resistance to erythromycin and clindamycin were higher in MRSA as compared to MSSA (erythromycin-resistance: 88.2% Vs 39.1% and clindamycin-resistance: 79.4% Vs 41.8%). The overall prevalence of
conclusionsDetection rate of MRSA in our study shows the necessity to improve in healthcare practices and to formulate new policy for the control of MRSA infections. Clindamycin resistance in the form of
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