ArticleNature neuroscience2017
Neural reactivations during sleep determine network credit assignment.
Article in Nature neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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Who cites it
67 citing papers in PubMed.
- Article
- Assistive algorithms influence neural representations in motor brain-computer interfaces.Nature communications · 2026Article
- Induction of cortical on/off periods in awake mice fulfills sleep functions.Nature neuroscience · 2026Article
- Brain-computer interfaces as a causal probe for scientific inquiry.Trends in cognitive sciences · 2026Review
- VTA dopaminergic neuronal activity during NREM sleep is modulated by learning and facilitates motor memory consolidation.Science advances · 2025Article
- Infant long-term memory: The last quarter century and the next.Infant behavior & development · 2025Review
- Induction of cortical ON/OFF periods in awake mice fulfills sleep functions.bioRxiv : the preprint server for biology · 2025Article
- Effective cerebellar neuroprosthetic control after stroke.Cell reports · 2025Article
- Neural Circuit Mapping and Neurotherapy-Based Strategies.Cellular and molecular neurobiology · 2025Review
- Assistive sensory-motor perturbations influence learned neural representations.bioRxiv : the preprint server for biology · 2025Article
- Article
- Coupling of Slow Oscillations in the Prefrontal and Motor Cortex Predicts Onset of Spindle Trains and Persistent Memory Reactivations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Slow-wave sleep drives sleep-dependent renormalization of synaptic AMPA receptor levels in the hypothalamus.PLoS biology · 2024Article
- Cortico-cerebellar coordination facilitates neuroprosthetic control.Science advances · 2024Article
- Spindle oscillations in communicating axons within a reconstituted hippocampal formation are strongest in CA3 without thalamus.Scientific reports · 2024Article
- Learning leaves a memory trace in motor cortex.Current biology : CB · 2024Article
- Emergence of task-related spatiotemporal population dynamics in transplanted neurons.Nature communications · 2023Article
- Disturbed laterality of non-rapid eye movement sleep oscillations in post-stroke human sleep: a pilot study.medRxiv : the preprint server for health sciences · 2023Article
- Emergence of cortical network motifs for short-term memory during learning.Nature communications · 2023Article
- Flexible regulation of representations on a drifting manifold enables long-term stable complex neuroprosthetic control.bioRxiv : the preprint server for biology · 2023Article
7 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
A fundamental goal of motor learning is to establish the neural patterns that produce a desired behavioral outcome. It remains unclear how and when the nervous system solves this 'credit assignment' problem. Using neuroprosthetic learning, in which we could control the causal relationship between neurons and behavior, we found that sleep-dependent processing was required for credit assignment and the establishment of task-related functional connectivity reflecting the casual neuron-behavior relationship. Notably, we observed a strong link between the microstructure of sleep reactivations and credit assignment, with downscaling of non-causal activity. Decoupling of spiking to slow oscillations using optogenetic methods eliminated rescaling. Thus, our results suggest that coordinated firing during sleep is essential for establishing sparse activation patterns that reflect the causal neuron-behavior relationship.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.