ArticleeLife2017
Ionic mechanisms underlying history-dependence of conduction delay in an unmyelinated axon.
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Probabilistic spike propagation shapes sympathetic output in mouse preganglionic neurons.bioRxiv : the preprint server for biology · 2026Article
- Biophysical properties of the membrane influence spike initiation dynamics and neuronal excitability: a focus on Kv1 channels in myelinated axons.Proceedings. Biological sciences · 2025Review
- The influence of hyperpolarization-activated cation current on conduction delay and failure of action potentials along axon related to abnormal functions.Cognitive neurodynamics · 2024Article
- A modelling study to dissect the potential role of voltage-gated ion channels in activity-dependent conduction velocity changes as identified in small fiber neuropathy patients.Frontiers in computational neuroscience · 2023Article
- Interactions among diameter, myelination, and the Na/K pump affect axonal resilience to high-frequency spiking.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Comodulation of h- and NaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Contributions of h- and NaFrontiers in cellular neuroscience · 2021Article
- Mutual Suppression of Proximal and Distal Axonal Spike Initiation Determines the Output Patterns of a Motor Neuron.Frontiers in cellular neuroscience · 2019Article
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Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Axonal conduction velocity can change substantially during ongoing activity, thus modifying spike interval structures and, potentially, temporal coding. We used a biophysical model to unmask mechanisms underlying the history-dependence of conduction. The model replicates activity in the unmyelinated axon of the crustacean stomatogastric pyloric dilator neuron. At the timescale of a single burst, conduction delay has a non-monotonic relationship with instantaneous frequency, which depends on the gating rates of the fast voltage-gated Na
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.