Evidence map›Paper›PMID 28691440›Full record

ArticleJournal of the International AIDS Society2017

High risk of loss to follow-up among South African children on ART during transfer, a retrospective cohort analysis with community tracing.

Chloe A Teasdale, Nonzwakazi Sogaula, Katharine A Yuengling, Zachary J Peters, Anthony Mutiti, Lungile Pepeta, Elaine J Abrams

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Incidence of Health Facility Switching and Associations With HIV Viral Rebound Among Persons on Antiretroviral Therapy in Uganda: A Population-based Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Using Observational Data to Inform HIV Policy Change for Children and Youth.Journal of acquired immune deficiency syndromes (1999) · 2018
    Observational
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Chloe A TeasdaleICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.
Nonzwakazi SogaulaICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.
Katharine A YuenglingICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.
Zachary J PetersICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.
Anthony MutitiICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.
Lungile PepetaPort Elizabeth Hospital Complex, Department of Paediatrics, Port Elizabeth, South Africa.
Elaine J AbramsICAP, Mailman School of Public Health, Columbia University, New York, NY, USA.
Columbia University · USPort Elizabeth Provincial Hospital · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDecentralization of HIV care for children has been recommended to improve paediatric outcomes by making antiretroviral treatment (ART) more accessible. We documented outcomes of children transferred after initiating ART at a large tertiary hospital in the Eastern Cape of South Africa.

methodsElectronic medical records for all children 0-15 years initiating ART at Dora Nginza Hospital (DNH) in Port Elizabeth, South Africa January 2004 to September 2015 were examined. Records for children transferred to primary and community clinics were searched at 16 health facilities to identify children with successful (at least one recorded visit) and unsuccessful transfer (no visits). We identified all children lost to follow-up (LTF) after ART initiation: those LTF at DNH (no visit >6 months), children with unsuccessful transfer, and children LTF after successful transfer (no visit >6 months). Community tracing was conducted to locate caregivers of children LTF and electronic laboratory data were searched to measure reengagement in care, including silent transfers.

results1,582 children initiated ART at median age of 4 years [interquartile range (IQR): 1-8] and median CD4+ of 278 cells/mm

conclusionWe found that only two-thirds of children on ART transferred to primary and community health clinics had successful transfer. These findings suggest that transfer is a particularly vulnerable step in the paediatric HIV care cascade.

Indexed as

Lost to Follow-UpAdolescentAmbulatory Care FacilitiesAnti-HIV AgentsBlack PeopleChildChild, PreschoolCohort StudiesFemaleFollow-Up StudiesHIV InfectionsHumansInfantInfant, NewbornMalePoliticsAnti-HIV AgentsARTdecentralizationloss to follow-uppaediatric HIVreferralretention

Identifiers

PMID28691440
PMCPMC5515030
OpenAlexW2728753402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.