Evidence map›Paper›PMID 28691024›Full record

ArticleBioMed research international2017

Self-Assembling RADA16-I Peptide Hydrogel Scaffold Loaded with Tamoxifen for Breast Reconstruction.

Huimin Wu, Ting Zhou, Lin Tian, Zhengchao Xia, Feng Xu

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Huimin WuFengxian Hospital, Southern Medical University, Shanghai 201400, China.
Ting ZhouFengxian Hospital, Southern Medical University, Shanghai 201400, China.
Lin TianThe Fifth Hospital, Sun Yat-sen University, Zhuhai 519000, China.
Zhengchao XiaFengxian Hospital, Southern Medical University, Shanghai 201400, China.
Feng XuFengxian Hospital, Southern Medical University, Shanghai 201400, China.ORCID 0000-0001-6215-8696
Southern Medical University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

More and more breast cancer patients prefer autologous fat tissue transfer following lumpectomy to maintain perfect female characteristics. However, the outcome was not satisfactory due to the transplanted fat absorption. In this study, we prepared two RADA16-I peptide scaffolds with and without tamoxifen. Both scaffolds were transparent, porous, and hemisphere-shaped. The hADSCs isolated from liposuction were attached to the scaffold. The growth inhibition of the hADSCs induced by TAM in 2-demensional (2D) culture was higher than that in TAM-loaded hydrogel scaffold 3D culture (

Indexed as

MammaplastyAdipogenesisAdipose TissueAnimalsApoptosisBody WeightCells, CulturedCell SeparationFemaleHumansHydrogel, Polyethylene Glycol DimethacrylateMCF-7 CellsMice, NudePeptidesSpectroscopy, Fourier Transform InfraredStem CellsHydrogel, Polyethylene Glycol DimethacrylatePeptidesRADA16-ITamoxifen

Identifiers

PMID28691024
PMCPMC5485292
OpenAlexW2625073063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.