Evidence map›Paper›PMID 28690677›Full record

ReviewEcancermedicalscience2017

The past and future of breast cancer treatment-from the papyrus to individualised treatment approaches.

Felipe Ades, Konstantinos Tryfonidis, Dimitrios Zardavas

Open access · goldAbstract readReview
In one paragraph

Review in Ecancermedicalscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Using [Cancers · 2025
    Article
  6. Article
  7. Article
  8. Presidential Address: A Long Time Ago in the Future.Annals of surgical oncology · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Overcoming Barriers in Ductal Carcinoma In Situ Management: From Overtreatment to Optimal Treatment.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022
    Article
  14. Review
  15. Article
  16. 100 Disruptive Publications in Breast Cancer Research.Asian Pacific journal of cancer prevention : APJCP · 2021
    Article
  17. Review
  18. The Use of Real-World Evidence for Oral Chemotherapies in Breast Cancer.Journal of the advanced practitioner in oncology · 2021
    Review
  19. Chemotherapy Treatment Considerations in Metastatic Breast Cancer.Journal of the advanced practitioner in oncology · 2021
    Review
  20. Long Noncoding RNAs Regulate the Radioresistance of Breast Cancer.Analytical cellular pathology (Amsterdam) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Felipe AdesHospital Albert Einstein, Avenida Albert Einstein, 627 - Morumbi, São Paulo - SP, 05652-900 Brazil.
Konstantinos TryfonidisEuropean Organisation for Research and Treatment of Cancer, Avenue E. Mounier 83/11, 1200 Brussels, Belgium.
Dimitrios ZardavasBreast International Group (BIG), Boulevard de Waterloo 76, Brussels 1000, Belgium.
Breast International Group · BEEuropean Organisation for Research and Treatment of Cancer · BEHospital Israelita Albert Einstein · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is one of the oldest diseases ever described, since ancient Egypt there have always been attempts to treat and cure this illness. The growing body of knowledge about breast cancer biology and improvements in surgical and medical treatments has been built over time with contributions from many talented and enthusiastic physicians and researchers. Medical advances have changed the approach from a previously incurable condition, into a surgical disease. Further improvements in cancer biology have allowed the development of systemic treatments, hormonal therapies, and targeted drugs. The description of the molecular intrinsic subtypes of breast cancer clarified the understanding of breast cancer as a group of heterogeneous diseases, associated with different clinical outcomes, and therapeutic opportunities. This paper reviews how breast cancer treatment has improved since the earliest descriptions, in ancient times, and how future approaches, such as gene signatures, molecular profiling, and liquid biopsies, aim to further develop individualised treatments and improve treatment outcomes.

Indexed as

breast cancerbreast surgerycancer historygene signatureliquid biopsymolecular profiling

Identifiers

PMID28690677
PMCPMC5481194
OpenAlexW2621493881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.