Evidence map›Paper›PMID 28690333›Full record

ArticleCellular & molecular immunology2018

Characterization and biological significance of IL-23-induced neutrophil polarization.

Yang Li, Linnan Zhu, Zhulang Chu, Tao Yang, Hai-Xi Sun, Fan Yang, Wei Wang, Yuzhu Hou, Peng Wang, Qingjie Zhao and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Cellular & molecular immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Target neutrophil heterogeneity and plasticity in cancer.Journal of hematology & oncology · 2025
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Research progress on the neutrophil components and their interactions with immune cells in the development of psoriasis.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. IL-17 AggravatesFrontiers in immunology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Yang LiState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, 100020, Beijing, China.
Linnan ZhuState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, 100020, Beijing, China.
Zhulang ChuState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, 100020, Beijing, China.
Tao YangState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, 100020, Beijing, China.
Hai-Xi SunState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, 100020, Beijing, China.
Fan YangState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, 100020, Beijing, China.
Wei WangDepartment of Urology, Beijing Chaoyang Hospital, Capital Medical University, 100020, Beijing, China.
Yuzhu HouState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, 100020, Beijing, China.
Peng WangState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, 100020, Beijing, China.
Qingjie ZhaoState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, 100020, Beijing, China.
Yaling TaoState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, 100020, Beijing, China.
Lianfeng ZhangKey Laboratory of Human Diseases Comparative Medicine, Ministry of Health, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Peking Union Medical College, 100021, Beijing, China. zhanglf@cnilas.org.
Xiaodong ZhangDepartment of Urology, Beijing Chaoyang Hospital, Capital Medical University, 100020, Beijing, China. zhangxiaodong@bjcyh.com.
Yong ZhaoState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, 100020, Beijing, China. zhaoy@ioz.ac.cn.
Chinese Academy of Sciences · CNInstitute of Zoology · CNCapital Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophils are heterogeneous with distinct subsets, and can switch phenotypes to exert regulatory functions on immunity. We herein demonstrate that IL-23-treated neutrophils selectively produce IL-17A, IL-17F and IL-22, and display a distinct gene expression profile in contrast to resting and lipopolysaccharide-treated neutrophils. IL-17

Indexed as

Cell PolarityAnimalsColitisCytokinesGene Expression ProfilingInterleukin-23Mice, Inbred BALB CMice, Inbred C57BLNeutrophilsSTAT3 Transcription FactorTh17 CellsCytokinesInterleukin-23STAT3 Transcription FactorcolitisIL-17IL-23inflammationneutrophilspolarization

Identifiers

PMID28690333
PMCPMC6068162
OpenAlexW2736243219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.