ArticleJournal of Ayurveda and integrative medicine
Antitumor effect of Ferula assa foetida oleo gum resin against breast cancer induced by 4T1 cells in BALB/c mice.
Article in Journal of Ayurveda and integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 63 citations in OpenAlex.
- A Comprehensive Review of the Anticancer Activity of Farnesiferol C and Umbelliferone.Anti-cancer agents in medicinal chemistry · 2026Review
- Effects of Limb Remote Ischemic Conditioning and Asafoetida on Biochemical, Histological, and Neurological Parameters and Metabolic Gene Expression in Diabetic Rats.Combinatorial chemistry & high throughput screening · 2026Article
- Effect of Ferula sp. on sperm cryotolerance, quality, and fatty acid composition in common carp (Cyprinus carpio).Veterinary research communications · 2025Article
- Ethnobotanical survey of medicinal plants used in management of breast cancers in Qatar.Heliyon · 2025Article
- A Review of Anticancer Activity ofCurrent pharmaceutical design · 2025Review
- Antiviral Effect ofCurrent pharmaceutical biotechnology · 2025Review
- Cytotoxic and apoptotic effects of Ferula gummosa Boiss: extract on human breast adenocarcinoma cell line.Molecular biology reports · 2024Article
- A Comprehensive Review of the Pharmacological Effects of Genus Ferula on Central Nervous System Disorders.Central nervous system agents in medicinal chemistry · 2024Review
- Antitumor and Phytochemical Properties ofMolecules (Basel, Switzerland) · 2023Article
- Review of potential spermatogenic and aphrodisiac effects of the Ferula genus.Clinical and experimental reproductive medicine · 2023Article
- Anticancer potential ofWorld journal of biological chemistry · 2023Review
- Therapeutic effect of Ferula assa-foetida oleo-gum resin in rats with letrozole-induced polycystic ovary syndrome.Clinical and experimental reproductive medicine · 2022Article
- Racemic Norlignans as Diastereoisomers fromMolecules (Basel, Switzerland) · 2022Article
- Nano-Drug Delivery Systems Entrapping Natural Bioactive Compounds for Cancer: Recent Progress and Future Challenges.Frontiers in oncology · 2022Review
- COVID-19, cytokines, inflammation, and spices: How are they related?Life sciences · 2021Review
- Antihypertensive Effects of Standardized Asafoetida: Effect on Hypertension Induced by Angiotensin II.Advanced biomedical research · 2020Article
- Preventive Effect ofInternational journal of preventive medicine · 2020Article
- Antibacterial and Cytotoxic Potential of Biosynthesized Silver Nanoparticles by Some Plant Extracts.Nanomaterials (Basel, Switzerland) · 2018Article
- Role of the potassium channels in vasorelaxant effect of asafoetida essential oil.Avicenna journal of phytomedicineArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFerula assa foetida commonly consumed as a healthy beverage has been demonstrated to have various biological activities, including antioxidation, anti-obesity and anti-cancer.
objectiveOur study aims to investigate the antitumor effect of asafoetida in vivo using mouse mammary carcinoma 4T1 cells. MATERIALS AND
methodsIn the study, female BALB/c mice were divided into two groups (n = 6), which were control (untreated) and other group of mice with breast cancer treated with 100 mg/kg of asafoetida, respectively, by oral gavage. All mice were injected into the mammary fat pad with 4T1 cells (1 × 10
resultsOur results showed that treatment with asafoetida was effective in decreasing the tumor weight and tumor volume in treated mice. Body weight significantly increased in female BALB/c mice against control. Apart from the antitumor effect, asafoetida decreased lung, liver and kidney metastasis and also increased areas of necrosis in the tumor tissue respectively.
conclusionsThe present study demonstrated that asafoetida has potent antitumor and antimetastasis effects on breast cancer and is a potential source of natural antitumor products.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.