ArticleHead and neck pathology2018
STAT6 Reliably Distinguishes Solitary Fibrous Tumors from Myofibromas.
Article in Head and neck pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Solitary fibrous tumor of the oral cavity: a systematic review of the literature and a new clinicopathologic case report.Frontiers in oral health · 2026Pooled it
- Subcutaneous Solitary Fibrous Tumor in the Chin of a Young Adult: A Diagnostic Challenge.The American journal of case reports · 2026Article
- Endoscopic resection of adult sphenoid sinus myofibroma: a rare case report with narrative review.Frontiers in oncology · 2026Article
- Case Report: Giant communicating solitary fibrous tumor of the temporal skull base and infratemporal fossa.Frontiers in surgery · 2026Article
- Solitary Fibrous Tumor Generated From Uterine Corpus With Doege-Potter Syndrome in Primary Disease: A Rare Case of Recurrent Disease Without Hypoglycemia.Case reports in obstetrics and gynecology · 2026Article
- Solitary fibrous tumor of the gallbladder: a case report.Surgical case reports · 2024Article
- Oral myofibroma presenting as an aggressive gingival lesion.BMJ case reports · 2021Article
- Aggressive Intraosseous Myofibroma of the Maxilla: Report of a Rare Case and Literature Review.Head and neck pathology · 2021Review
- Cellular solitary fibrous tumor in the mental area: a case report and literature review.The Journal of international medical research · 2021Review
- Solitary fibrous tumor.Translational gastroenterology and hepatology · 2018Review
- A Solitary Fibrous Tumor of the Eyelid.Pakistan journal of medical sciencesArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Solitary fibrous tumors (SFT) and myofibromas (MF) historically have belonged to the same morphologic spectrum and have been lumped together under the nonspecific umbrella term, "hemangiopericytoma" along with other pericytic/myoid tumors. While current evidence shows clear distinction between the two entities, they frequently remain in the same histopathologic differential diagnosis. This diagnostic dilemma especially is common for smaller incisional biopsies from the oral cavity. STAT6 immunohistochemistry (IHC) recently was established as a reliable method to detect solitary fibrous tumor; however, the literature is sparse regarding STAT6 reactivity in MFs. The authors report ten new cases of oral solitary fibrous tumor, discuss histopathologic similarities and differences between the two tumors, and list respective STAT6 IHC expressivity. After IRB approval, 10 cases diagnosed as SFT and 24 cases of MF were collected from the University of Florida Oral and Maxillofacial Pathology Biopsy Service between the years 1994 and 2016. The original hematoxylin and eosin slides and related IHC were reviewed. IHC with STAT6 antibody was performed on all 34 samples, and the findings were analyzed. All cases were from the oral cavity or perioral regions. 10/10 SFTs expressed STAT6 nuclear reactivity, while no cases of MF showed nuclear expression of STAT6. STAT6 is a dependable marker to differentiate SFTs from MFs.
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