Evidence map›Paper›PMID 28689255›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2017

Identification of morin as an agonist of imidazoline I-3 receptor for insulin secretion in diabetic rats.

Mang Hung Lin, Chia-Chen Hsu, Jenshinn Lin, Juei-Tang Cheng, Ming Chang Wu

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mang Hung LinDepartment of Food Science, College of Agriculture, National Pingtung University of Science and Technology, Pingtung City, Taiwan, 90801.
Chia-Chen HsuDepartment of Food Science, College of Agriculture, National Pingtung University of Science and Technology, Pingtung City, Taiwan, 90801.
Jenshinn LinDepartment of Food Science, College of Agriculture, National Pingtung University of Science and Technology, Pingtung City, Taiwan, 90801.
Juei-Tang ChengDepartment of Medical Research, Chi-Mei Medical Center, Yong Kang, Tainan City, Taiwan, 73101. jtcheng@mail.cjcu.edu.tw.
Ming Chang WuDepartment of Food Science, College of Agriculture, National Pingtung University of Science and Technology, Pingtung City, Taiwan, 90801. globalizationwu@yahoo.com.tw.
National Pingtung University of Science and Technology · TWChang Jung Christian University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Morin is a flavonoid contained in guava that is known to reduce hyperglycemia in diabetics. Morin has been demonstrated to increase plasma insulin. However, the mechanism(s) remains unknown. The present study is designed to investigate the effect of morin on the imidazoline receptor (I-R) that regulates insulin secretion. We used Chinese hamster ovary (CHO) cells transfected with an I-R expression construct (NISCH-CHO-K1 cells) to identify the direct effect of morin on the I-R. Moreover, the imidazoline I

Indexed as

AnimalsAntioxidantsBenzofuransCHO CellsCricetinaeCricetulusDiabetes Mellitus, ExperimentalDose-Response Relationship, DrugFlavonesFlavonoidsImidazolesImidazoline ReceptorsInsulinInsulin SecretionIslets of LangerhansMaleAntioxidantsBenzofuransFlavonesFlavonoidsImidazolesImidazoline ReceptorsInsulinKU 14RmorinCHO cellsImidazoline I3 receptorInsulin secretionMorinNISCH

Identifiers

PMID28689255
OpenAlexW2732007705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.