Evidence map›Paper›PMID 28689246›Full record

ReviewParasitology research2017

Parasites and asthma.

Lin Wuhao, Chen Ran, He Xujin, Wu Zhongdao, Paron Dekumyoy, Lv Zhiyue

Abstract readReview
PubMed Publisher
In one paragraph

Review in Parasitology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Bugs as drugs: parasite biomolecules as novel therapeutics against breast cancer.American journal of physiology. Cell physiology · 2026
    Review
  2. Article
  3. Review
  4. Frontiers in pharmacology · 2020
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Lin WuhaoZhongshan School of Medicine, Sun Yat-sen University, 74 2nd Zhongshan Road, Guangzhou, 510080, China.
Chen RanZhongshan School of Medicine, Sun Yat-sen University, 74 2nd Zhongshan Road, Guangzhou, 510080, China.
He XujinThe Affiliated High School of South China Normal University, Guangzhou, 510630, China.
Wu ZhongdaoZhongshan School of Medicine, Sun Yat-sen University, 74 2nd Zhongshan Road, Guangzhou, 510080, China.
Paron DekumyoyFaculty of Tropical Medicine, Mahidol University, Bangkok, 10400, Thailand. paron.dek@mahidol.ac.th.
Lv ZhiyueZhongshan School of Medicine, Sun Yat-sen University, 74 2nd Zhongshan Road, Guangzhou, 510080, China. lvzhiyue@mail.sysu.edu.cn.
Sun Yat-sen University · CNMahidol Oxford Tropical Medicine Research Unit · THSouth China Normal University · CN

Funding

the National Key Research and Development Program of China 2016YFC1202003, 2016YFC1202005
6 · The paper itself

Abstract

Nowadays, many studies have found low morbidity of asthma in epidemic areas of parasitic diseases, as shown by the hygiene hypothesis. It is obvious that some parasite infections can prevent asthma and studies have been carried out to clarify the mechanism of the preventive effect and search for the future asthmatic therapies. Previous findings have indicated that this mechanism may be related to the immune response switching from Th1 to Th2 and important cells induced by parasites, including the regulatory T cells, regulatory B cells, dendrite cells, and alternatively activated macrophages. Cytokine IL-10 also plays a nonredundant role in protection against allergic airway inflammation in asthma. This review focuses on the relationship between parasites and asthma, and the potential protection mechanism involved.

Indexed as

AnimalsAsthmaB-Lymphocytes, RegulatoryDendritic CellsHumansInterleukin-10Macrophage ActivationMacrophagesMiceParasitesParasitic DiseasesTh1 CellsTh2 CellsT-Lymphocytes, RegulatoryIL10 protein, humanInterleukin-10AsthmaParasitePreventionTherapy

Identifiers

PMID28689246
OpenAlexW2726637346

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.