Observational studyGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2017
Insights into autofluorescence patterns in Stargardt macular dystrophy using ultra-wide-field imaging.
Observational study in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Clinical application of ultra-widefield fundus autofluorescence.International ophthalmology · 2021Pooled it
- Stargardt-like Clinical Characteristics and Disease Course Associated with Variants in theGenes · 2023Article
- Automated Segmentation of Autofluorescence Lesions in Stargardt Disease.Ophthalmology. Retina · 2022Article
- Ultra-wide field retinal imaging: A wider clinical perspective.Indian journal of ophthalmology · 2021Review
- Correlation of Morphology and Function of Flecks Using Short-Wave Fundus Autofluorescence and Microperimetry in Patients With Stargardt Disease.Translational vision science & technology · 2021Article
- Utility of pattern recognition and multimodal imaging in the diagnosis and management of doyne honeycomb retinal dystrophy complicated with type one choroidal neovascular membrane.BMJ case reports · 2021Article
- Reviewing the Role of Ultra-Widefield Imaging in Inherited Retinal Dystrophies.Ophthalmology and therapy · 2020Review
- Insights into retinal hemangioblastoma using ultra widefield imaging.Indian journal of ophthalmology · 2019Article
- Clinic-based ultra-wide field retinal imaging in a pediatric population.International journal of retina and vitreous · 2019Article
- The role of multimodal imaging and vision function testing inTherapeutic advances in ophthalmologyReview
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo characterize autofluorescence (AF) patterns occurring in Stargardt macular dystrophy (STGD1) using ultra-wide-field (UWF) imaging.
methodsThis paper is a cross-sectional observational study of 22 eyes of 11 patients (mean age 23.44 years) with Stargardt disease-fundus flavimaculatus who presented with decrease of vision at a tertiary eye care center. UWF short-wave AF images were obtained from all the patients using an Optos TX200 instrument. The main outcome measures were to assess patterns of AF changes seen on UWF AF imaging.
resultsAll eyes showed a central area of hypoautofluorescence at the macula along with retinal flecks extending centrifugally as well as to the nasal side of the optic disc. Peripapillary sparing was seen in 100% of the eyes. Flecks were seen to be hypoautofluorescent in the center and hyperautofluorescent in the periphery in 77.8% eyes and were only hyperfluorescent in 27.2%. A background-increased fluorescence was visible in 100% of eyes, the outer boundary of which was marked by distribution of flecks in 81.9% eyes. A characteristic inferonasal vertical line was seen separating the nasal hypoautofluorescent area from the temporal hyperautofluorescent area in all the eyes.
conclusionsUWF AF changes in STGD1 are not limited to the posterior pole and may extend more peripherally. UWF imaging is a useful tool for the assessment of patients with Stargardt macular dystrophy.
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Registered trials
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