Evidence map›Paper›PMID 28687970›Full record

ArticleFamilial cancer2018

Association of genetic variations in RTN4 3'-UTR with risk for clear cell renal cell carcinoma.

Yan Pu, Peng Chen, Bin Zhou, Peng Zhang, Yanyun Wang, Yaping Song, Lin Zhang

Abstract read
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In one paragraph

Article in Familial cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yan PuDepartment of Forensic Biology, West China School of Basic Sciences and Forensic Medicine, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China.
Peng ChenDepartment of Forensic Medicine, Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.
Bin ZhouLaboratory of Molecular Translational Medicine, West China Institute of Women and Children's Health, Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Peng ZhangDepartment of Urology, West China Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Yanyun WangLaboratory of Molecular Translational Medicine, West China Institute of Women and Children's Health, Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Yaping SongLaboratory of Molecular Translational Medicine, West China Institute of Women and Children's Health, Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, People's Republic of China.
Lin ZhangDepartment of Forensic Biology, West China School of Basic Sciences and Forensic Medicine, Sichuan University, Chengdu, 610041, Sichuan, People's Republic of China. zhanglin@scu.edu.cn.
Sichuan University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nogo proteins play an important role in the apoptosis of cells, especially in tumor cells. The present study was conducted to evaluate whether the TATC (rs71682980) and CAA (rs34917480) insertion/deletion polymorphisms of RTN4 3'-UTR are associated with clear cell renal cell carcinoma (ccRCC). These two polymorphisms were genotyped in 308 ccRCC patients and 466 healthy controls by polymerase chain reaction polyacrylamide gel electrophoresis (PCR-PAGE). Significantly reduced ccRCC risk was observed to be associated with the TATC

Indexed as

Genetic Predisposition to Disease3' Untranslated RegionsAdultAgedAged, 80 and overAsian PeopleCarcinoma, Renal CellCase-Control StudiesFemaleHumansINDEL MutationKidney NeoplasmsMaleMiddle AgedNogo ProteinsPolymorphism, Genetic3' Untranslated RegionsNogo ProteinsRTN4 protein, humanClear cell renal cell carcinomaGenetic susceptibilityNogo proteinsPolymorphismRTN4

Identifiers

PMID28687970
OpenAlexW2724212452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.