ArticleDigestive diseases and sciences2017
Symptoms of Functional Intestinal Disorders Are Common in Patients with Celiac Disease Following Transition to a Gluten-Free Diet.
Article in Digestive diseases and sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.
- Irritable Bowel Syndrome and Gluten-Related Disorders.Nutrients · 2020Pooled it
- Trial
- Clinical and Histopathological Profile of Adults with Celiac Disease at Diagnosis and on a Gluten-Free Diet: A Cross-Sectional Observational Study.Clinics and practice · 2026Article
- Endoscopy and noninvasive tests in pediatric disorders of gut-brain interaction: A multicenter retrospective study of the Italian Society of Pediatric Gastroenterology, Hepatology, and Nutrition.Journal of pediatric gastroenterology and nutrition · 2025Article
- Challenges in the Pediatric Celiac Disease Diagnosis: An Up-to-Date Review.Diagnostics (Basel, Switzerland) · 2025Review
- Rome Foundation Working Team Report on overlap in disorders of gut-brain interaction.Nature reviews. Gastroenterology & hepatology · 2025Review
- FODMAP Diet in Celiac Disease and Gluten-Related Disorders.Nutrients · 2024Review
- Celiac disease symptom profiles and their relationship to gluten-free diet adherence, mental health, and quality of life.BMC gastroenterology · 2024Observational
- The Gluten-Free Diet for Celiac Disease: Critical Insights to Better Understand Clinical Outcomes.Nutrients · 2023Review
- The Role of Gluten in Gastrointestinal Disorders: A Review.Nutrients · 2023Review
- Review article: Follow-up of coeliac disease.Alimentary pharmacology & therapeutics · 2022Review
- Persistent symptoms are diverse and associated with health concerns and impaired quality of life in patients with paediatric coeliac disease diagnosis after transition to adulthood.BMJ open gastroenterology · 2022Article
- Dyspepsia-Like Symptoms inInternational journal of general medicine · 2022Article
- Systematic Review of Pediatric Functional Gastrointestinal Disorders (Rome IV Criteria).Journal of clinical medicine · 2021Review
- Article
- The Role of Diet in Functional Dyspepsia Management.Frontiers in psychiatry · 2020Review
- Functional Dyspepsia in the Elderly.Current gastroenterology reports · 2019Review
- A Retrospective Study on Dietary FODMAP Intake in Celiac Patients Following a Gluten-Free Diet.Nutrients · 2018Article
- The distribution of HLA DQ2 and DQ8 haplotypes and their association with health indicators in a general Danish population.United European gastroenterology journal · 2018Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundCeliac disease and functional intestinal disorders may overlap, yet the natural history of functional symptoms in patients with celiac disease is unknown.
aimTo investigate the prevalence of irritable bowel syndrome (IBS), functional dyspepsia (FD), and functional bloating (FB) symptoms among patients with celiac disease at diagnosis and during the first year of a gluten-free diet.
methodsAdults with a new diagnosis of celiac disease were surveyed at baseline, 6 months and 1 year using standardized measures for intestinal symptoms [Rome III diagnostic questionnaire and celiac symptom index (CSI)] and gluten-free diet adherence [gluten-free eating assessment tool (GF-EAT) and celiac diet adherence test].
resultsAt diagnosis, two-thirds fulfilled Rome III diagnostic questionnaire symptom criteria for IBS (52%), functional dyspepsia (27%), and/or functional bloating (9%). One year post-diagnosis, there was high adherence to a gluten-free diet as 93% reported gluten exposure less than once per month on the GF-EAT and only 8% had ongoing celiac disease symptoms (CSI score >45). The rates of those meeting IBS (22%) and functional dyspepsia (8%) symptom criteria both decreased significantly on a gluten-free diet. The prevalence of functional symptoms (any of IBS, FD or FB) at 1 year was 47%.
conclusionsLong-term follow-up of patients with celiac disease is necessary because many patients with celiac disease who are adherent to a gluten-free diet have persistent gastrointestinal symptoms.
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Registered trials
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