Evidence map›Paper›PMID 28687907›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2017

Functional activation of Gα

Yuji Odagaki, Masakazu Kinoshita, Toshio Ota, J Javier Meana, Luis F Callado, Jesús A García-Sevilla

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neural transmission (Vienna, Austria : 1996), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Functional coupling of MEuropean archives of psychiatry and clinical neuroscience · 2020
    Article
  6. Functional coupling between adenosine APurinergic signalling · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Yuji OdagakiDepartment of Psychiatry, Faculty of Medicine, Saitama Medical University, 38 Morohongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan. odagaki@saitama-med.ac.jp.ORCID 0000-0002-1792-028X
Masakazu KinoshitaDepartment of Psychiatry, Faculty of Medicine, Saitama Medical University, 38 Morohongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan.
Toshio OtaDepartment of Psychiatry, Faculty of Medicine, Saitama Medical University, 38 Morohongo, Moroyama-machi, Iruma-gun, Saitama, 350-0495, Japan.
J Javier MeanaDepartment of Pharmacology, University of the Basque Country, UPV/EHU, 48940, Leioa, Bizkaia, Spain.
Luis F CalladoDepartment of Pharmacology, University of the Basque Country, UPV/EHU, 48940, Leioa, Bizkaia, Spain.
Jesús A García-SevillaLaboratory of Neuropharmacology, IUNICS/IdISPa, University of the Balearic Islands (UIB), Palma de Mallorca, Spain.
Saitama Medical University · JPUniversity of the Basque Country · ESResearch Institute of Health Sciences · ESSaitama Medical University Hospital · JP

Funding

Saitama University Internal Grant 26B-1-12; 16-B-1-11Spanish MINECO-FEDER SAF 2009-08460Spanish MINECO-FEDER SAF 2011-29918Spanish MINECO-FEDER SAF 2013-48586-R
6 · The paper itself

Abstract

Heterotrimeric guanine nucleotide-binding proteins (G-proteins) play a pivotal role in a wide range of signal transduction pathways, and receptor/G-protein coupling has been implicated in the pathophysiology of mental disorders. In this study, guanosine-5'-O-(3-[

Indexed as

AdolescentAdultAgedAged, 80 and overCerebral CortexDose-Response Relationship, DrugFemaleGTP-Binding Protein alpha Subunits, Gq-G11HumansMaleMembranesMiddle AgedNeurotransmitter AgentsReceptor, Muscarinic M1Receptor, Serotonin, 5-HT2AYoung AdultGTP-Binding Protein alpha Subunits, Gq-G11Neurotransmitter AgentsReceptor, Muscarinic M1Receptor, Serotonin, 5-HT2A[35S]GTPγS binding5-HT2A receptorG-proteinImmunoprecipitationMuscarinic acetylcholine receptorPostmortem human brain

Identifiers

PMID28687907
OpenAlexW2730400469

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.