Evidence map›Paper›PMID 28687740›Full record

ArticleScientific reports2017

Organization and hierarchy of the human functional brain network lead to a chain-like core.

Rossana Mastrandrea, Andrea Gabrielli, Fabrizio Piras, Gianfranco Spalletta, Guido Caldarelli, Tommaso Gili

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Contrastive Brain Network Learning via Hierarchical Signed Graph Pooling Model.IEEE transactions on neural networks and learning systems · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rossana MastrandreaIMT School for Advanced Studies, Lucca, piazza S. Ponziano 6, 55100, Lucca, Italy. rossana.mastrandrea@imtlucca.it.
Andrea GabrielliIMT School for Advanced Studies, Lucca, piazza S. Ponziano 6, 55100, Lucca, Italy.
Fabrizio PirasEnrico Fermi Center, Piazza del Viminale 1, 00184, Rome, Italy.
Gianfranco SpallettaIRCCS Fondazione Santa Lucia, Via Ardeatina 305, 00179, Rome, Italy.
Guido CaldarelliIMT School for Advanced Studies, Lucca, piazza S. Ponziano 6, 55100, Lucca, Italy.ORCID 0000-0001-9377-3616
Tommaso GiliEnrico Fermi Center, Piazza del Viminale 1, 00184, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The brain is a paradigmatic example of a complex system: its functionality emerges as a global property of local mesoscopic and microscopic interactions. Complex network theory allows to elicit the functional architecture of the brain in terms of links (correlations) between nodes (grey matter regions) and to extract information out of the noise. Here we present the analysis of functional magnetic resonance imaging data from forty healthy humans at rest for the investigation of the basal scaffold of the functional brain network organization. We show how brain regions tend to coordinate by forming a highly hierarchical chain-like structure of homogeneously clustered anatomical areas. A maximum spanning tree approach revealed the centrality of the occipital cortex and the peculiar aggregation of cerebellar regions to form a closed core. We also report the hierarchy of network segregation and the level of clusters integration as a function of the connectivity strength between brain regions.

Indexed as

AdultBrainFemaleHealthy VolunteersHumansMagnetic Resonance ImagingMaleMiddle AgedNerve Net

Identifiers

PMID28687740
PMCPMC5501790

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.