ArticleScientific reports2017
A possible origin population of pathogenic intestinal nematodes, Strongyloides stercoralis, unveiled by molecular phylogeny.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 102 citations in OpenAlex.
- Prevalence of Strongyloides in Southeast Asia: a systematic review and meta-analysis with implications for public health and sustainable control strategies.Infectious diseases of poverty · 2023Pooled it
- From the feces to the genome: a guideline for the isolation and preservation of Strongyloides stercoralis in the field for genetic and genomic analysis of individual worms.Parasites & vectors · 2019Guideline
- Strongyloides Genetic Diversity among Humans, Dogs, and Nonhuman Primates, Central African Republic, 2016-2022.Emerging infectious diseases · 2026Article
- Retrospective screening reveals the rare occurrence of zoonoticParasitology · 2026Article
- Taxonomy ofParasitology · 2026Review
- Molecular taxonomic characterisation ofFrontiers in parasitology · 2026Article
- Molecular taxonomic study ofFrontiers in parasitology · 2026Article
- Zoonotic Risk of Intestinal Parasites in Ghana's Protected Areas: A Nexus for Human-Nonhuman Primates-Dog Interactions.Journal of parasitology research · 2026Article
- Strongyloides species exhibit distinct behaviors on the skin of different mammals.BMC infectious diseases · 2025Article
- Human, canine and feline strongyloidiasis: beyondParasitology · 2025Review
- A population genetic analysis of the nematodeProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Prevalence of strongyloidiasis in immunocompromised patients in Mazandaran province of northern Iran: A comprehensive study utilizing simultaneous parasitological, serological, and molecular techniques.Parasite epidemiology and control · 2025Article
- Feline strongyloidiasis: An insight into its global prevalence and transmission cycle.One health (Amsterdam, Netherlands) · 2024Review
- A scoping review of transmission models for soil-transmitted helminth infections to underpin the development of a transmission model forParasitology · 2024Article
- Genomic analysis of Strongyloides stercoralis and Strongyloides fuelleborni in Bangladesh.PLoS neglected tropical diseases · 2024Article
- A Pilot Study for the Characterization ofMicroorganisms · 2024Article
- High-throughput sequencing ofParasitology · 2024Article
- Strongyloides stercoralis genotyping in a human population in southwestern Iran.Parasites & vectors · 2024Article
- Review
- Is strongyloidiasis a zoonosis from dogs?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
Corrections and comments
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Authors and funding
27 authors at 8 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Humans and dogs are the two major hosts of Strongyloides stercoralis, an intestinal parasitic nematode. To better understand the phylogenetic relationships among S. stercoralis isolates infecting humans and dogs and to assess the zoonotic potential of this parasite, we analyzed mitochondrial Cox1, nuclear 18S rDNA, 28S rDNA, and a major sperm protein domain-containing protein genes. Overall, our analyses indicated the presence of two distinct lineages of S. stercoralis (referred to as type A and type B). While type A parasites were isolated both from humans and dogs in different countries, type B parasites were found exclusively in dogs, indicating that the type B has not adapted to infect humans. These epidemiological data, together with the close phylogenetic relationship of S. stercoralis with S. procyonis, a Strongyloides parasite of raccoons, possibly indicates that S. stercoralis originally evolved as a canid parasite, and later spread into humans. The inability to infect humans might be an ancestral character of this species and the type B might be surmised to be an origin population from which human-infecting strains are derived.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.