Evidence map›Paper›PMID 28687643›Full record

ArticleCMAJ open2017

Cancer incidence attributable to lifestyle and environmental factors in Alberta in 2012: summary of results.

Anne Grundy, Abbey E Poirier, Farah Khandwala, Xin Grevers, Christine M Friedenreich, Darren R Brenner

Abstract read
In one paragraph

Article in CMAJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anne GrundyAffiliations: Department of Cancer Epidemiology and Prevention Research (Grundy, Poirier, Khandwala, Grevers, Friedenreich, Brenner), CancerControl Alberta, Alberta Health Services, Edmonton, Alta.; Department of Oncology (Friedenreich, Brenner) and Department of Community Health Sciences (Friedenreich, Brenner), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Abbey E PoirierAffiliations: Department of Cancer Epidemiology and Prevention Research (Grundy, Poirier, Khandwala, Grevers, Friedenreich, Brenner), CancerControl Alberta, Alberta Health Services, Edmonton, Alta.; Department of Oncology (Friedenreich, Brenner) and Department of Community Health Sciences (Friedenreich, Brenner), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Farah KhandwalaAffiliations: Department of Cancer Epidemiology and Prevention Research (Grundy, Poirier, Khandwala, Grevers, Friedenreich, Brenner), CancerControl Alberta, Alberta Health Services, Edmonton, Alta.; Department of Oncology (Friedenreich, Brenner) and Department of Community Health Sciences (Friedenreich, Brenner), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Xin GreversAffiliations: Department of Cancer Epidemiology and Prevention Research (Grundy, Poirier, Khandwala, Grevers, Friedenreich, Brenner), CancerControl Alberta, Alberta Health Services, Edmonton, Alta.; Department of Oncology (Friedenreich, Brenner) and Department of Community Health Sciences (Friedenreich, Brenner), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Christine M FriedenreichAffiliations: Department of Cancer Epidemiology and Prevention Research (Grundy, Poirier, Khandwala, Grevers, Friedenreich, Brenner), CancerControl Alberta, Alberta Health Services, Edmonton, Alta.; Department of Oncology (Friedenreich, Brenner) and Department of Community Health Sciences (Friedenreich, Brenner), Cumming School of Medicine, University of Calgary, Calgary, Alta.
Darren R BrennerAffiliations: Department of Cancer Epidemiology and Prevention Research (Grundy, Poirier, Khandwala, Grevers, Friedenreich, Brenner), CancerControl Alberta, Alberta Health Services, Edmonton, Alta.; Department of Oncology (Friedenreich, Brenner) and Department of Community Health Sciences (Friedenreich, Brenner), Cumming School of Medicine, University of Calgary, Calgary, Alta.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEstimates of the proportion of cancer cases that can be attributed to modifiable risk factors are not available for Canada and, more specifically, Alberta. The purpose of this study was to estimate the total proportion of cancer cases in Alberta in 2012 that could be attributed to a set of 24 modifiable lifestyle and environmental risk factors.

methodsWe estimated summary population attributable risk estimates for 24 risk factors (smoking [both passive and active], overweight and obesity, inadequate physical activity, diet [inadequate fruit and vegetable consumption, inadequate fibre intake, excess red and processed meat consumption, salt consumption, inadequate calcium and vitamin D intake], alcohol, hormones [oral contraceptives and hormone therapy], infections [Epstein-Barr virus, hepatitis B and C viruses, human papillomavirus,

resultsOverall, an estimated 40.8% of cancer cases in Alberta in 2012 were attributable to modifiable lifestyle and environmental risk factors. The largest proportion of cancers were estimated to be attributable to tobacco smoking, physical inactivity and excess body weight. The summary population attributable risk estimate was slightly higher among women (42.4%) than among men (38.7%).

interpretationAbout 41% of cancer cases in Alberta may be attributable to known modifiable lifestyle and environmental risk factors. Reducing the prevalence of these factors in the Alberta population has the potential to substantially reduce the provincial cancer burden.

Identifiers

PMID28687643
PMCPMC5621951

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.