Evidence map›Paper›PMID 28687602›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2017

Imaging B Cells in a Mouse Model of Multiple Sclerosis Using

Michelle L James, Aileen Hoehne, Aaron T Mayer, Kendra Lechtenberg, Monica Moreno, Gayatri Gowrishankar, Ohad Ilovich, Arutselvan Natarajan, Emily M Johnson, Joujou Nguyen and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. [Communications biology · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Contribution of Intravital Neuroimaging to Study Animal Models of Multiple Sclerosis.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Longitudinal Imaging of T Cells and Inflammatory Demyelination in a Preclinical Model of Multiple Sclerosis UsingJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Neuroinflammation PET Imaging: Current Opinion and Future Directions.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Michelle L JamesDepartment of Radiology, Stanford University, Stanford, California.
Aileen HoehneDepartment of Radiology, Stanford University, Stanford, California.
Aaron T MayerDepartment of Radiology, Stanford University, Stanford, California.
Kendra LechtenbergDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, California; and.
Monica MorenoDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, California; and.
Gayatri GowrishankarDepartment of Radiology, Stanford University, Stanford, California.
Ohad IlovichDepartment of Radiology, Stanford University, Stanford, California.
Arutselvan NatarajanDepartment of Radiology, Stanford University, Stanford, California.
Emily M JohnsonDepartment of Radiology, Stanford University, Stanford, California.
Joujou NguyenDepartment of Radiology, Stanford University, Stanford, California.
Lisa QuachDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, California; and.
May HanDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, California; and.
Marion BuckwalterDepartment of Neurology and Neurological Sciences, Stanford University, Stanford, California; and.
Sudeep ChandraClinical and Translational Imaging, Department of Translational Medicine, Novartis Institute of Biomedical Research, Cambridge, Massachusetts.
Sanjiv S GambhirDepartment of Radiology, Stanford University, Stanford, California sgambhir@stanford.edu.
Stanford University · US

Funding

Predoctoral Training in Biomedical Imaging at Stanford UniversityT32EB009653 · NIBIB · STANFORD UNIVERSITY · PI BUTTS-PAULY, KIM · 2010 to 2019
$2.1M
NIBIB NIH HHS T32 EB009653
6 · The paper itself

Abstract

B lymphocytes are a key pathologic feature of multiple sclerosis (MS) and are becoming an important therapeutic target for this condition. Currently, there is no approved technique to noninvasively visualize B cells in the central nervous system (CNS) to monitor MS disease progression and response to therapies. Here, we evaluated

Indexed as

B-LymphocytesRadiopharmaceuticalsAnimalsAutoradiographyBrainCopper RadioisotopesEncephalomyelitis, Autoimmune, ExperimentalHumansMiceMice, Inbred C57BLMice, TransgenicMultiple SclerosisPositron-Emission TomographyRituximabSpinal CordTissue DistributionCopper RadioisotopesRadiopharmaceuticalsRituximabB cellsEAEmultiple sclerosisPETrituximab

Identifiers

PMID28687602
PMCPMC5666646
OpenAlexW2733827979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.