Evidence map›Paper›PMID 28687226›Full record

ReviewTrends in cardiovascular medicine2017

Acquired long QT syndrome and phosphoinositide 3-kinase.

Ira S Cohen, Richard Z Lin, Lisa M Ballou

Abstract readReview
In one paragraph

Review in Trends in cardiovascular medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Modulating the voltage sensor of a cardiac potassium channel shows antiarrhythmic effects.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  4. Article
  5. Review
  6. Article
  7. AnFrontiers in pharmacology · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ira S CohenDepartment of Physiology and Biophysics, The Institute for Molecular Cardiology, Stony Brook University, Stony Brook, NY. Electronic address: ira.cohen@stonybrook.edu.
Richard Z LinDepartment of Physiology and Biophysics, The Institute for Molecular Cardiology, Stony Brook University, Stony Brook, NY; Medical Service, Northport VA Medical Center, Northport, NY.
Lisa M BallouDepartment of Physiology and Biophysics, The Institute for Molecular Cardiology, Stony Brook University, Stony Brook, NY.
Stony Brook University · USNorthport VA Medical Center · US

Funding

MANIPULATING IKS AS A THERAPEUTIC APPROACH TO CARDIAC ARRHYTHMIASR01HL126774 · NHLBI · WASHINGTON UNIVERSITY · PI CUI, JIANMIN · 2015 to 2018
$3.1M
PI3K Signaling and Channelopathies in the HeartR01DK108989 · NIDDK · STATE UNIVERSITY NEW YORK STONY BROOK · PI LIN, RICHARD Z · 2016 to 2019
$1.8M
NHLBI NIH HHS R01 HL126774NIDDK NIH HHS R01 DK108989
6 · The paper itself

Abstract

While it is well known that mutation of several different ion channels can cause congenital long QT syndrome, block of I

Indexed as

Phosphoinositide-3 Kinase InhibitorsAction PotentialsAnimalsHeart Conduction SystemHeart RateHumansLong QT SyndromePhosphatidylinositol 3-KinasePotassium Channel BlockersProtein Kinase InhibitorsRisk FactorsSodium Channel BlockersPhosphatidylinositol 3-KinasePhosphoinositide-3 Kinase InhibitorsPotassium Channel BlockersProtein Kinase InhibitorsSodium Channel BlockersdiabetesdofetilideLong QT syndromephosphoinositide 3-kinasesodium current

Identifiers

PMID28687226
PMCPMC5582013
OpenAlexW2615994392

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.