ArticleAmerican journal of surgery2017
Increased pancreatic cancer survival with greater lymph node retrieval in the National Cancer Data Base.
Article in American journal of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Reassessing the role of lymph node dissection in pancreatic cancer surgery: Balancing oncologic control and immune function preservation.World journal of gastrointestinal oncology · 2025Review
- Optimal Number of Lymph Nodes Retrieved to Lower the Risk of False N0 for Patients with Pancreatic Cancer Undergoing Curative Surgery.Annals of surgical oncology · 2025Article
- Prognostic significance of grade of malignancy based on histopathological differentiation and Ki-67 in pancreatic ductal adenocarcinoma.Cancer biology & medicine · 2024Article
- A new staging system for postoperative prognostication in pancreatic ductal adenocarcinoma.iScience · 2023Article
- Exploration of the lymphadenectomy strategy for elderly pancreatic ductal adenocarcinoma patients undergoing curative-intent resection.American journal of cancer research · 2023Article
- Presence of tumor deposits is an indicator of poor prognosis in patients with pancreatic ductal adenocarcinoma.American journal of cancer research · 2023Article
- The prognostic relevance of examined lymph nodes for accurate staging of resected pancreatic adenocarcinoma.Hepatobiliary surgery and nutrition · 2022Article
- Article
- Review
- A National Assessment of Optimal Oncologic Surgery for Distal Pancreatic Adenocarcinomas.Pancreas · 2021Article
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- Role of lymphadenectomy, adjuvant chemotherapy, and treatment at high-volume centers in patients with resected pancreatic cancer-a distinct view on lymph node yield.Langenbeck's archives of surgery · 2020Article
- Management of pancreatic head adenocarcinoma: From where to where?World journal of gastrointestinal surgery · 2019Review
- Prognostic value of the metastatic lymph node ratio in patients with pancreatic cancer.International journal of clinical and experimental pathology · 2019Article
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7 authors.
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Abstract
backgroundWe evaluated the role of lymph node (LN) retrieval in pancreatic adenocarcinoma (PA) patients undergoing pancreaticoduodenectomy (PD).
methodsWe utilized the National Cancer Data Base; Cox regression models and logistic regression models were used for statistical evaluation.
resultsWe evaluated 26,792 patients with PA who underwent PD. The mean LN retrieved in LN(-) patients was 10.8 vs 14.4 for LN(+) patients (P < 0.0001). Greater LN retrieval is an independent predictor of a negative microscopic margin and decreased length of stay. The median survival of LN(-) patients exceeded that of LN(+) patients (24.5 vs 15.1 months, P < 0.0001). Increasing LN retrieval is a significant predictor of survival in all patients, and in LN(-) patients. The relationship of increased LN retrieval and enhanced survival is a nearly linear trend.
conclusionsRather than demonstrating an inflection point that defines the extent of adequate lymphadenectomy, this dataset demonstrates an incremental relationship between LN retrieval and survival.
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