Evidence map›Paper›PMID 28686950›Full record

ArticleEnvironmental research2017

Residential proximity to agricultural fumigant use and IQ, attention and hyperactivity in 7-year old children.

Robert B Gunier, Asa Bradman, Rosemary Castorina, Nina T Holland, Dylan Avery, Kim G Harley, Brenda Eskenazi

Abstract read
In one paragraph

Article in Environmental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Robert B GunierCenter for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA, USA. Electronic address: gunier@berkeley.edu.
Asa BradmanCenter for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA, USA.
Rosemary CastorinaCenter for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA, USA.
Nina T HollandCenter for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA, USA.
Dylan AveryCenter for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA, USA.
Kim G HarleyCenter for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA, USA.
Brenda EskenaziCenter for Environmental Research and Children's Health (CERCH), School of Public Health, University of California, Berkeley, CA, USA.

Funding

Project C: Epigenetic Effects of DDT/E and PBDEs on PubertyP01ES009605 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI ESKENAZI, BRENDA · 1999 to 2015
$11.2M
PON Epigenetics and Neurodevelopment in ChildrenR01ES023067 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI HOLLAND, NINA T · 2014 to 2017
$1.3M
Current-use fumigants: Health effects of prenatal and early childhood exposuresR56ES023591 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BRADMAN, ASA · 2014 to 2014
$322k
NIEHS NIH HHS P01 ES009605NIEHS NIH HHS R01 ES023067NIEHS NIH HHS R56 ES023591
6 · The paper itself

Abstract

objectivesOur objective was to examine the relationship between residential proximity to agricultural fumigant use and neurodevelopment in 7-year old children.

methodsParticipants were living in the agricultural Salinas Valley, California and enrolled in the Center for the Health Assessment of Mothers and Children Of Salinas (CHAMACOS) study. We administered the Wechsler Intelligence Scale for Children (4th Edition) to assess cognition and the Behavioral Assessment System for Children (2nd Edition) to assess behavior. We estimated agricultural fumigant use within 3, 5 and 8km of residences during pregnancy and from birth to age 7 using California's Pesticide Use Report data. We evaluated the association between prenatal (n = 285) and postnatal (n = 255) residential proximity to agricultural use of methyl bromide, chloropicrin, metam sodium and 1,3-dichloropropene with neurodevelopment.

resultsWe observed decreases of 2.6 points (95% Confidence Interval (CI): -5.2, 0.0) and 2.4 points (95% CI: -4.7, -0.2) in Full-Scale intelligence quotient for each ten-fold increase in methyl bromide and chloropicrin use within 8km of the child's residences from birth to 7-years of age, respectively. There were no associations between residential proximity to use of other fumigants and cognition or proximity to use of any fumigant and hyperactivity or attention problems. These findings should be explored in larger studies.

Indexed as

Intelligence TestsAttentionCaliforniaChildFemaleFumigationHumansHyperkinesisLongitudinal StudiesPesticidesPregnancyPrenatal Exposure Delayed EffectsPesticidesBehaviorChildrenFumigantsNeurodevelopmentPesticides

Identifiers

PMID28686950
PMCPMC5557382

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.