Evidence map›Paper›PMID 28686869›Full record

ArticleCell stem cell2017

Modeling the Glomerular Filtration Barrier: Are You Kidney-ing Me?

Paola Romagnani, Laura Lasagni

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell stem cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Progress and breakthroughs in human kidney organoid research.Biochemistry and biophysics reports · 2024
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Paola RomagnaniExcellence Centre for Research, Transfer and High Education for the development of DE NOVO Therapies (DENOTHE) and Department of Biomedical, Experimental and Clinical Sciences 'Mario Serio', University of Florence, 50121 Florence, Italy; Pediatric Nephrology Unit, Meyer Children's Hospital, University of Florence, 50139 Florence, Italy. Electronic address: paola.romagnani@unifi.it.
Laura LasagniExcellence Centre for Research, Transfer and High Education for the development of DE NOVO Therapies (DENOTHE) and Department of Biomedical, Experimental and Clinical Sciences 'Mario Serio', University of Florence, 50121 Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Podocyte depletion drives kidney disease and kidney failure progression, but podocyte complexity at the glomerular filtration barrier is difficult to model in vitro. In Nature Biomedical Engineering, Musah et al. (2017) developed a multifluidic device with iPS-derived podocytes mimicking a functional glomerular filtration barrier that elevates standards for modeling glomerular diseases.

Indexed as

Models, BiologicalAnimalsHumansInduced Pluripotent Stem CellsKidney DiseasesPodocytes

Identifiers

PMID28686869

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.