Evidence map›Paper›PMID 28686817›Full record

ArticleArthritis care & research2018

Affect and Incident Participation Restriction in Adults With Knee Osteoarthritis.

Molly W Vaughan, Michael P LaValley, David T Felson, Gael I Orsmond, Jingbo Niu, Cora E Lewis, Neil A Segal, Michael C Nevitt, Julie J Keysor

Abstract readMulticenter Study
In one paragraph

Article in Arthritis care & research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Molly W VaughanBoston University, Boston, Massachusetts.
Michael P LaValleyBoston University, Boston, Massachusetts.
David T FelsonBoston University, Boston, Massachusetts.
Gael I OrsmondBoston University, Boston, Massachusetts.
Jingbo NiuBaylor College of Medicine, Houston, Texas.
Cora E LewisUniversity of Alabama, Birmingham.
Neil A SegalUniversity of Kansas Medical Center, Kansas City.
Michael C NevittUniversity of California, San Francisco.
Julie J KeysorBoston University, Boston, Massachusetts.

Funding

Multicenter Osteoarthritis Study (MOST) Second Renewal - Boston UniversityU01AG018820 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI FELSON, DAVID TOBIN · 2001 to 2019
$13.6M
NIA NIH HHS U01 AG018820
6 · The paper itself

Abstract

objectiveParticipation restriction, common among people with knee osteoarthritis (OA), may be influenced by affect. We examined the risk of incident participation restriction over 84 months conferred by positive and negative affect among people with knee OA.

methodsParticipants were from the Multicenter Osteoarthritis Study and had or were at high risk of knee OA. Participation restriction was measured using the Instrumental Role Limitation subscale of the Late-Life Disability Index, and affect was measured using the positive affect and depressed mood subscales of the Center for Epidemiologic Studies Depression Scale. Robust Poisson regression was used to calculate the risk of incident participation restriction over 84 months conferred by combinations of low and high positive and negative affect, adjusting for covariates.

resultsOf 1,810 baseline participants (mean age 62.1 years, 56% female), 470 (26%) had incident participation restriction over 84 months. Participants with low positive affect had 20% greater risk of incident participation restriction than those with high positive affect; participants with high negative affect had 50% greater risk of incident participation restriction compared to those with low negative affect. Participants with both low positive and high negative affect had 80% greater risk of incident participation restriction compared to other combinations of positive and negative affect.

conclusionLow positive and high negative affect, both alone and in combination, increase the risk of participation restriction among adults with knee OA. Efforts aimed at preventing participation restriction in this population should consider these mood states.

Indexed as

AffectSocial ParticipationActivities of Daily LivingAgedAlabamaBiomechanical PhenomenaCost of IllnessDisability EvaluationFemaleHumansIowaKnee JointLongitudinal StudiesMaleMiddle AgedOsteoarthritis, Knee

Identifiers

PMID28686817
PMCPMC6492559

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.