Evidence map›Paper›PMID 28686231›Full record

ArticlePLoS medicine2017

Antimicrobial resistance in Neisseria gonorrhoeae: Global surveillance and a call for international collaborative action.

Teodora Wi, Monica M Lahra, Francis Ndowa, Manju Bala, Jo-Anne R Dillon, Pilar Ramon-Pardo, Sergey R Eremin, Gail Bolan, Magnus Unemo

Registry-linked trialAbstract read
In one paragraph

Article in PLoS medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07758972 (A First in Human Phase I Randomized and Controlled Trial to Test Safety and Immunogenicity of a Multivalent Vaccine Against Neisseria Gonorrhoeae), which is not on this map. Cited by 309 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
309citing papers in PubMed, 15 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07758972 phase1recruitingnot on this mapstarted 2026, after this paper: background citation

A First in Human Phase I Randomized and Controlled Trial to Test Safety and Immunogenicity of a Multivalent Vaccine Against Neisseria Gonorrhoeae

TypeinterventionalSponsorLimmaTech Biologics AGRan2026 to 2027Enrolled142ConditionsNeisseria GonorrheaArmsLTB-NG6, Sodium Chloride 0.9%
3 · Its place in the literature

Who cites it

309 citing papers in PubMed, 15 syntheses or guidelines pooled it.

  1. Antimicrobial Resistance inMedicina (Kaunas, Lithuania) · 2026
    Pooled it
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  5. A systematic review of Neisseria gonorrhoeae drug resistance development in South Africa.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Pooled it
  6. Pooled it
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  8. Epidemiology of gonorrhoea: systematic review, meta-analyses, and meta-regressions, World Health Organization European Region, 1949 to 2021.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Pooled it
  9. The frequency of mutations in theFrontiers in microbiology · 2024
    Pooled it
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  14. Surveillance systems to monitor antimicrobial resistance inEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2022
    Pooled it
  15. Global epidemiology ofSexually transmitted infections · 2021
    Pooled it
  16. Trial
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249 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Teodora WiDepartment of Reproductive Health and Research, World Health Organization, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-7640-9166
Monica M LahraWorld Health Organization Collaborating Centre for Sexually Transmitted Diseases, New South Wales Health Pathology, Sydney, Australia.
Francis NdowaSkin and Genitourinary Medicine Clinic, Harare, Zimbabwe.
Manju BalaApex Regional STD Teaching, Training & Research Centre, VMMC and Safdarjung Hospital, New Delhi, India.
Jo-Anne R DillonUniversity of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID http://orcid.org/0000-0002-4351-666X
Pilar Ramon-PardoCommunicable Disease Analysis, World Health Organization, Washington, D.C., United States of America.ORCID http://orcid.org/0000-0002-4862-2568
Sergey R EreminAntimicrobial Resistance Secretariat, World Health Organization, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-0486-3255
Gail BolanDivision of STD Prevention, Centers for Disease Control and Prevention, Georgia, Atlanta, United States of America.
Magnus UnemoWorld Health Organization Collaborating Centre for Gonorrhoea and other STIs, Örebro University, Örebro, Sweden.ORCID http://orcid.org/0000-0003-1710-2081

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a Policy Forum, Teodora Wi and colleagues discuss the challenges of antimicrobial resistance in gonococci.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsEpidemiological MonitoringGlobal HealthGonorrheaHumansNeisseria gonorrhoeaeAnti-Bacterial Agents

Identifiers

PMID28686231
PMCPMC5501266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.