ArticleInternational journal of molecular sciences2017
Immunological and Inflammatory Impact of Non-Intubated Lung Metastasectomy.
Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
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Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Non-intubated anesthesia in patients undergoing video-assisted thoracoscopic surgery: A systematic review and meta-analysis.PloS one · 2019Pooled it
- Pooled it
- Comparison of early postoperative cytokine changes in patients undergoing intubated and non-intubated thoracic surgery: a randomized controlled trial.Interactive cardiovascular and thoracic surgery · 2021Trial
- Activation of PI3K/Akt/HIF-1α Signaling is Involved in Lung Protection of Dexmedetomidine in Patients Undergoing Video-Assisted Thoracoscopic Surgery: A Pilot Study.Drug design, development and therapy · 2020Trial
- Impact of Awake Breast Cancer Surgery on Postoperative Lymphocyte Responses.In vivo (Athens, Greece)Trial
- Effects of non-intubated anesthesia on postoperative pulmonary complications after thoracoscopic segmentectomy: a propensity score-matched analysis.Annals of medicine · 2026Article
- Review
- Role of PBAF and Mediator kinase module in the RELA-dependent activation ofFrontiers in immunology · 2026Article
- Non-intubated uniportal video-assisted thoracoscopic anatomical lung volume reduction surgery-an institutional report.Journal of thoracic disease · 2025Article
- From Awake to Minimalist Spontaneous Ventilation Thoracoscopic Lung Surgery: An Ongoing Journey.Journal of clinical medicine · 2025Article
- Current New Approach in Thoracoscopic Surgery: Non-Intubated Uniportal Video-Assisted Thoracoscopic Surgery (NI-UniVATS).Medicina (Kaunas, Lithuania) · 2025Article
- Did the Coronavirus Disease 2019 (COVID-19) Pandemic Cause a Delay in the Diagnosis of Breast Cancer Patients?Cureus · 2024Article
- Chronic postoperative pain after non-intubated uniportal VATS lobectomy.Frontiers in surgery · 2023Article
- Clinical application of intubation-free anesthesia in radical resection of lung cancer.Frontiers in medicine · 2023Article
- Anesthetic (r)evolution from the conventional concept to the minimally invasive techniques in thoracic surgery-narrative review.Journal of thoracic disease · 2022Review
- Perioperative Inflammatory Response and Cancer Recurrence in Lung Cancer Surgery: A Narrative Review.Frontiers in surgery · 2022Review
- Pathophysiological Advantages of Spontaneous Ventilation.Frontiers in surgery · 2022Review
- Current Status and Prospects of Anesthesia and Breast Cancer: Does Anesthetic Technique Affect Recurrence and Survival Rates in Breast Cancer Surgery?Frontiers in oncology · 2022Review
- Perioperative Systemic Inflammation in Lung Cancer Surgery.Frontiers in surgery · 2022Review
- Results of redo pulmonary metastasectomy.Journal of thoracic disease · 2021Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe hypothesized that video-assisted thoracic surgery (VATS) lung metastasectomy under non-intubated anesthesia may have a lesser immunological and inflammatory impact than the same procedure under general anesthesia.
methodsBetween December 2005 and October 2015, 55 patients with pulmonary oligometastases (at the first episode) successfully underwent VATS metastasectomy under non-intubated anesthesia. Lymphocytes subpopulation and interleukins 6 and 10 were measured at different intervals and matched with a control group composed of 13 patients with similar clinical features who refused non-intubated surgery.
resultsThe non-intubated group demonstrated a lesser reduction of natural killer lymphocytes at 7 days from the procedure (
conclusionsVATS lung metastasectomy in non-intubated anesthesia had significantly lesser impact on both immunological and inflammatory response compared to traditional procedure in intubated general anesthesia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.