ReviewChinese medical journal2017
Radiation Therapy in Keloids Treatment: History, Strategy, Effectiveness, and Complication.
Review in Chinese medical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed.
- Trial
- Post-surgical electron beam radiotherapy for prevention of keloid recurrence: A retrospective study of 619 cases demonstrating low recurrence (6.5%) with optimised 18 Gy in two fractions.Clinical medicine (London, England) · 2026Article
- A Holistic Approach to Unravel Keloid Pathogenesis and Optimize Therapeutic Outcomes.Biomedicines · 2026Review
- Review
- USP37-stabilized SALL4 promotes the keloid formation by PI3K/AKT pathway.Scientific reports · 2025Article
- Sandwich Therapy with Radionuclide Combined with Intralesional Injections Based on Differences in the Spatial Structure Components of Keloids.Aesthetic plastic surgery · 2025Article
- Comparison of Predictive Models for Keloid Recurrence Based on Machine Learning.Journal of cosmetic dermatology · 2025Article
- Application of Remote Buried Dermal Super-Tension-Reducing Sutures for Incisional Scar Prevention.Clinical, cosmetic and investigational dermatology · 2025Article
- Wound Infection After Keloid Excision and Adjuvant Radiotherapy: Two Case Reports and Literature Review.Clinical, cosmetic and investigational dermatology · 2025Article
- Comprehensive Insights into Keloid Pathogenesis and Advanced Therapeutic Strategies.International journal of molecular sciences · 2024Review
- Application and effect of tension-reducing suture in surgical treatment of hypertrophic scar.BMC surgery · 2024Article
- The efficacy of sequentially comprehensive treatment based on surgery in the treatment of keloids: a retrospective study.Frontiers in medicine · 2024Article
- Future Directions About Keloid Scars Based on Pathogenesis and Therapies.Clinical, cosmetic and investigational dermatology · 2024Review
- Mapping variation of extracellular matrix in human keloid scar by label-free multiphoton imaging and machine learning.Journal of biomedical optics · 2023Article
- Impact of internal mammary artery perforator propeller flaps combined with radiotherapy in the treatment of large chest keloids: Our experience.Frontiers in surgery · 2023Article
- Vascular and Collagen Target: A Rational Approach to Hypertrophic Scar Management.Advances in wound care · 2023Review
- Scar-centered dilation in the treatment of large keloids.World journal of clinical cases · 2022Article
- Optimizing surgical outcome of auricular keloid with a novel multimodal approach.Scientific reports · 2022Article
- The outcome of postoperative radiation therapy following plastic surgical resection of recurrent ear keloid: a single institution experience.Journal of the Egyptian National Cancer Institute · 2022Article
- Current advances in the selection of adjuvant radiotherapy regimens for keloid.Frontiers in medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveRadiation therapy combined with surgical excision was considered as one of the most effective treatment plans for keloid lesions. However, there was no unanimity found over present literatures regarding the issue on optimized treatment strategy for keloids. We here provide a comprehensive review over this issue and emphasize on the influencing factors. DATA SOURCES: The data analyzed in this review were searched from articles included in PubMed and EMBASE databases. STUDY SELECTION: The original articles and critical reviews discussing the application of radiation therapy in keloids treatment were selected for this review.
resultsThe application of radiation therapy has transitioned from simple superficial X-ray irradiation to brachytherapy. Furthermore, several factors including radiation type, dose, fraction, interval, and complications were reviewed, and the results revealed that these factors were significant toward clinical outcome at various levels.
conclusionsBoth past and present evidence support the idea that combination therapy of radiation and surgical therapy is safe and feasible. However, the optimization of treatment strategy was based on different radiation types and should take dose, fractions, interval, and complications into consideration, which will then decrease the rate of recurrence and increase the level of satisfaction.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.