Evidence map›Paper›PMID 28685403›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2017

The change of cervical spine alignment along with aging in asymptomatic population: a preliminary analysis.

Yiwei Chen, Jiaquan Luo, Zhimin Pan, Limin Yu, Long Pang, Junlong Zhong, Zhiyun Li, Zhimin Han, Kai Cao

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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Sagittal balance of the cervical spine: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021
    Pooled it
  2. Which parameters are relevant in sagittal balance analysis of the cervical spine? A literature review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2018
    Pooled it
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  7. Age-related changes in cervical sagittal alignment: based on 625 Chinese asymptomatic subjects.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023
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  11. Variation of cervical sagittal alignment parameters according to gender, pelvic incidence and age.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yiwei ChenSpine Surgery, Orthopaedics Department, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Jiaquan LuoSpine Surgery, Orthopaedics Department, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Zhimin PanSpine Surgery, Orthopaedics Department, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Limin YuOrthopaedic Surgery, Beijing University Shenzhen Hospital, Shenzhen, 518036, China.
Long PangSpine Surgery, Orthopaedics Department, General Hospital of Ningxia Medical University, Ningxia, 750004, China.
Junlong ZhongSpine Surgery, Orthopaedics Department, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Zhiyun LiSpine Surgery, Orthopaedics Department, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Zhimin HanSpine Surgery, Orthopaedics Department, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China.
Kai CaoSpine Surgery, Orthopaedics Department, The First Affiliated Hospital of Nanchang University, Nanchang, 330006, China. kaichaw@126.com.

Funding

5511 innovation-driven program of Jiangxi Province Department of Science and Technology 20165BCB18017Key Program of Jaingxi Provincial Department of Science and Technology 20152ACB21024National Natural Science Foundation of China (CN) 81460405Research Program of Health and Family Planning Commission of Jiangxi Province 20155087Research Program of Health and Family Planning Commission of Jiangxi Province 20155110
6 · The paper itself

Abstract

STUDY

designA cross-sectional study.

objectiveTo investigate the correlation of cervical spine alignment changes with aging in asymptomatic population.

backgroundPrevious studies demonstrated the influence of lumbar and thoracic spine on cervical spine alignment, but few has reported the cervical spine alignment change along with aging in asymptomatic population.

methodsAsymptomatic population were divided into four groups according to different ages (Group A: ≤20 years; Group B: 21-40 years; Group C: 41-60 years; Group D: ≥61 years). Each group was composed of 30 subjects. The following parameters were measured: C0-1 Cobb angle, C1-2 Cobb angle, C2-7 Cobb angle, C1-7 sagittal vertical axis (C1-7 SVA), C2-7 SVA, central of gravity to C7 sagittal vertical axis (CG-C7 SVA), Thoracic Inlet Angle (TIA), Neck Tilt (NT), cervical tilt, cranial tilt, T1 slope (TS), TS-CL, and ANOVA statistical method was used to analyze the differences among four groups, and then, linear regression analysis was performed to analyze correlation of the cervical spine alignment with the aging.

resultsC1-7 SVA, C2-7 SVA, CG-C7 SVA, TIA, NT, TS, and cranial tilt were found statistically different among four groups (P < 0.01). From Group A to Group D, the mean C1-7 SVA were 30.7, 26.0, 21.8, and 36.9 mm, the mean C2-7 SVA were 18.7, 14.7, 11.9, and 24.7 mm, and the mean CG-C7 SVA were 19.6, 16.6, 9.4, and 26.7 mm. The mean TIA were 62.4°, 65.0°, 71.8°, and 76.9°, the mean NT were 39.4°, 43.8°, 46.3°, and 48.2°, the mean TS were 23.0°, 21.1°, 25.5°, and 28.7°, and the mean cranial tilt were 5.7°, 4.8°, 3.0°, and 9.5°. Further linear regression indicated that TIA (r = 0.472; P < 0.0001), NT (r = 0.337; P = 0.0006), and TS (r = 0.299; P = 0.0025) were positively correlated with aging.

conclusionA gradual increase of TIA, NT, and TS, accompanied with an increased CL, is found along with aging in asymptomatic population, among which TIA, NT, and TS are significantly correlated with physiological nature of aging.

Indexed as

AdolescentAdultAgedAged, 80 and overAgingCervical VertebraeChildCross-Sectional StudiesDisability EvaluationFemaleHumansMaleMiddle AgedNeckRadiographySkullAgingAsymptomatic populationCervical spine alignmentRadiology

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.