Evidence map›Paper›PMID 28685387›Full record

ReviewJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2017

Postoperative Abdominal Adhesions: Clinical Significance and Advances in Prevention and Management.

Demetrios Moris, Jeffery Chakedis, Amir A Rahnemai-Azar, Ana Wilson, Mairead Marion Hennessy, Antonios Athanasiou, Eliza W Beal, Chrysoula Argyrou, Evangelos Felekouras, Timothy M Pawlik

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07280286 (Incidence of Intrauterine Adhesions Following Myomectomies With the Use of an Intrauterine Anti-adhesion Gel), which is not on this map. Cited by 72 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed, 3 pooled it
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07280286 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Incidence of Intrauterine Adhesions Following Myomectomies With the Use of an Intrauterine Anti-adhesion Gel

TypeinterventionalSponsorFederico II UniversityRan2025 to 2028Enrolled62ConditionsMyoma, Uterus, Adhesion, Uterus, InternalArmsWomen will receive the application of an anti-adhesion gel at the end of the myomectomy procedure
3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 3 syntheses or guidelines pooled it, 170 citations in OpenAlex.

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12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Demetrios MorisDepartment of Surgery, Ohio State University, Wexner Medical Center, 395 W. 12th Ave., Suite 670, Columbus, OH, USA.
Jeffery ChakedisDepartment of Surgery, Ohio State University, Wexner Medical Center, 395 W. 12th Ave., Suite 670, Columbus, OH, USA.
Amir A Rahnemai-AzarDepartment of Surgery, University of Washington Medical Center, Seattle, WA, USA.
Ana WilsonDepartment of Surgery, Ohio State University, Wexner Medical Center, 395 W. 12th Ave., Suite 670, Columbus, OH, USA.
Mairead Marion HennessyDepartment of Surgery, Mercy University Hospital, Grenville Pl, Cork, Ireland.
Antonios AthanasiouDepartment of Surgery, Mercy University Hospital, Grenville Pl, Cork, Ireland.
Eliza W BealDepartment of Surgery, Ohio State University, Wexner Medical Center, 395 W. 12th Ave., Suite 670, Columbus, OH, USA.
Chrysoula Argyrou1st Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Evangelos Felekouras1st Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Timothy M PawlikDepartment of Surgery, Ohio State University, Wexner Medical Center, 395 W. 12th Ave., Suite 670, Columbus, OH, USA. Tim.Pawlik@osumc.edu.
The Ohio State University Wexner Medical Center · USMercy University Hospital · IELaiko General Hospital of Athens · GRNational and Kapodistrian University of Athens · GRUniversity of Washington Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postoperative adhesions remain one of the more challenging issues in surgical practice. Although peritoneal adhesions occur after every abdominal operation, the density, time interval to develop symptoms, and clinical presentation are highly variable with no predictable patterns. Numerous studies have investigated the pathophysiology of postoperative adhesions both in vitro and in vivo. Factors such as type and location of adhesions, as well as timing and recurrence of adhesive obstruction remain unpredictable and poorly understood. Although the majority of postoperative adhesions are clinically silent, the consequences of adhesion formation can represent a lifelong problem including chronic abdominal pain, recurrent intestinal obstruction requiring multiple hospitalizations, and infertility. Moreover, adhesive disease can become a chronic medical condition with significant morbidity and no effective therapy. Despite recent advances in surgical techniques, there is no reliable strategy to manage postoperative adhesions. We herein review the pathophysiology and clinical significance of postoperative adhesions while highlighting current techniques of prevention and treatment.

Indexed as

Postoperative ComplicationsAbdomenHumansPeritoneal DiseasesTissue AdhesionsAdhesionsComplicationsPeritonealReview

Identifiers

PMID28685387
OpenAlexW2726402512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.