ReviewObesity surgery2017
The Role of Endoscopic Intra-Gastric Botulinum Toxin-A for Obesity Treatment.
Review in Obesity surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- EUS-Guided Intragastric Injection of Botulinum Toxin A in the Preoperative Treatment of Super-Obese Patients: a Randomized Clinical Trial.Obesity surgery · 2019Trial
- Article
- Microneedle-Mediated Treatment of Obesity.Pharmaceutics · 2025Review
- Evaluating the efficacy of intragastric botulinum toxin a injections with two different quantities and sites for obesity.PloS one · 2025Article
- Effects of Intraparietal Gastric Botulinum Toxin-A Injection on Weight Loss: A Retrospective Study of 500 Patients.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Intragastric botulinum toxin injection for weight loss: current trends, shortcomings and future perspective.Clinical endoscopy · 2025Review
- The Controversy Surrounding Botulinum Neurotoxin (BONT) as a Weight Loss Intervention in Turkish Healthcare Realities.Obesity surgery · 2024Article
- Layer-Specific BTX-A Delivery to the Gastric Muscularis Achieves Effective Weight Control and Metabolic Improvement.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Effect of Intragastric Botulinum Type A Injection Combined with a Low-Calorie High-Protein Diet in Adults with Overweight or Obesity.Journal of clinical medicine · 2022Article
- Impact of Vagotomy on Postoperative Weight Loss, Alimentary Intake, and Enterohormone Secretion After Bariatric Surgery in Experimental Translational Models.Obesity surgery · 2022Article
- Is Intragastric Botulinum Toxin A Injection Effective in Obesity Treatment?Surgery research and practice · 2020Article
- Endoscopic bariatric therapies for treating obesity: a learning curve for gastroenterologists.Translational gastroenterology and hepatology · 2019Review
- The Forgotten Fundus-Response to - Obesity Treatment with Botulinum Toxin-A Is Not Effective: a Systematic Review and Meta-analysis.Obesity surgery · 2018Article
- Comparison of safety and efficacy of intragastric botulinum toxin-A versus gastric balloon.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology AssociationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity prevalence has been increasing with devastating health and economic consequences. Botulinum toxin type A (BTX-A), a neurotoxin, is used clinically for conditions characterized by prolonged muscular contraction. Its inhibitory effects on gastric smooth muscles, in theory, make it a potential agent for obesity treatment through delayed gastric emptying and increased satiety. This review aims to examine the evidence for the use of endoscopic BTX-A injection for treating obesity. The literature search identified 60 articles with 11 primary studies as relevant for the scope of the review. Several studies have been conducted to examine the effect of BTX-A injections on obesity, including both animal and human studies. Current evidence from identified studies does not demonstrate sustained weight loss through the use of endoscopic BTX-A injection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.