Trial reportObesity surgery2018
Bariatric Surgery Promising in Migraine Control: a Controlled Trial on Weight Loss and Its Effect on Migraine Headache.
Trial report in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- Effects of Surgical and Non-surgical Weight Loss on Migraine Headache: a Systematic Review and Meta-Analysis.Obesity surgery · 2020Pooled it
- The Effect of Bariatric Surgery on Migraines: a Systematic Review and Meta-analysis.Obesity surgery · 2020Pooled it
- Can upper cervical manual therapy affect the blink reflex in subjects with migraine and neck pain?The Journal of manual & manipulative therapy · 2024Trial
- Vitamin D3 might improve headache characteristics and protect against inflammation in migraine: a randomized clinical trial.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Trial
- The effects of vitamin D supplementation on interictal serum levels of calcitonin gene-related peptide (CGRP) in episodic migraine patients: post hoc analysis of a randomized double-blind placebo-controlled trial.The journal of headache and pain · 2020Trial
- Behavioral Weight Loss Intervention for Migraine: A Randomized Controlled Trial.Obesity (Silver Spring, Md.) · 2018Trial
- Short-Term Changes in Migraine Burden After Roux-en-Y Gastric Bypass: A Prospective Cohort Study.Obesity surgery · 2026Article
- Effect of Bariatric Surgery on Migraine Headache: A Systematic Review and Meta-Analysis.Cureus · 2025Review
- Changes in P2X4 receptor expression following AbobotulinumtoxinA treatment in patients with chronic migraine: A case series study.Current journal of neurology · 2025Article
- Forecasting migraine attacks by managing daily lifestyle: a systematic review as a basis to develop predictive algorithms.Pain reports · 2025Article
- The Association Between Body Fat Percentage and Severe Headache or Migraine: A National Cross-Sectional Survey.Cureus · 2024Article
- The association between adherence to alternative healthy Diet Index (AHEI) and severity, disability, duration, and frequency of migraine headache among women: a cross-sectional study.Nutrition journal · 2023Article
- Increased serum prolactin level may indicate more migraine attack frequency.Brain and behavior · 2023Article
- Bariatric Surgery in Migraine patients: CGRP Level and Weight Loss.Obesity surgery · 2022Article
- Prescriptions for pain medication before and after bariatric surgery.Surgical endoscopy · 2022Article
- B vitamins and their combination could reduce migraine headaches: A randomized double-blind controlled trial.Current journal of neurology · 2022Article
- Assessment of peripheral biomarkers potentially involved in episodic and chronic migraine: a case-control study with a focus on NGF, BDNF, VEGF, and PGE2.The journal of headache and pain · 2022Article
- The association between dairy intake and migraine odds among pediatrics and adolescents: A case-control study.Iranian journal of child neurology · 2022Article
- Migraine management: Non-pharmacological points for patients and health care professionals.Open medicine (Warsaw, Poland) · 2022Review
- The Association Between Dietary Acid Load and Odds of Migraine: A Case-Control Survey.Neurology and therapy · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
introductionThere is evidence that substantial weight loss through bariatric surgery (BS) may result in short-term improvement of migraine severity. However, it still remains to be seen whether smaller amounts of weight loss have a similar effect on migraine headache. This study has been designed to compare the effects of weight reduction through BS and non-surgical modifications. MATERIALS AND
methodsMigraine characteristics were assessed at 1 month before (T0), 1 month (T1), and 6 months (T2) after BS (vertical sleeve gastrectomy (VSG) (n = 25) or behavioral therapy (BT) (n = 26) in obese women (aged 18-60 years) with migraine headache. Migraine was diagnosed using the International Classification of Headache Disorders (ICHDIIβ) criteria.
resultsThere was significant reduction in the visual analog scale (VAS) from the baseline to T1 and T2 in both groups. The number of migraine-free days showed a significant increase within each group (p < 0.001). The BS group had a significant reduction in attack duration (p < 0.001) while there were no changes observed within the BT group. Following the adjustment of ANCOVA models for baseline values of migraine characteristics, age, changes in weight, BMI, body fat, and fat-free mass from T0 to T2, the BS group showed statistically significant lower VAS and duration of migraine attacks and a significantly higher number of migraine-free days than the BT group at T1 and T2 (p ≤ 0.028).
conclusionOur results indicated that far before significant weight reduction after BS (VSG), there was marked alleviation in the severity and duration of migraine and a significant increase in the number of migraine-free days in obese female migraineurs. However, the effects in the BT group were not comparable with the effects in the BS group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.