Evidence map›Paper›PMID 28685258›Full record

ArticleThe journal of headache and pain2017

Migraine and the risk of post-traumatic stress disorder among a cohort of pregnant women.

Lauren E Friedman, Christina Aponte, Rigoberto Perez Hernandez, Juan Carlos Velez, Bizu Gelaye, Sixto E Sánchez, Michelle A Williams, B Lee Peterlin

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in The journal of headache and pain, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06788977 (CEFALY Pregnancy Registry), which is not on this map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06788977 recruitingnot on this mapstarted 2024, after this paper: background citation

CEFALY Pregnancy Registry

Typeobservational_patient_registrySponsorCefaly TechnologyRan2024 to 2030Enrolled550ConditionsPregnancy, Migraine, Headache, PostpartumArmsexternal Trigeminal Nerve Stimulation
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Lauren E FriedmanDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, 677 Huntington Ave, K501, Boston, MA, 02115, USA. lfriedm@hsph.harvard.edu.
Christina AponteMultidisciplinary International Research Training Program, Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Rigoberto Perez HernandezMultidisciplinary International Research Training Program, Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Juan Carlos VelezDepartamento de Rehabilitación, Hospital del Trabajador, Santiago, Chile.
Bizu GelayeDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, 677 Huntington Ave, K501, Boston, MA, 02115, USA.
Sixto E SánchezUniversidad Peruana de Ciencias Aplicadas, Lima, Peru.
Michelle A WilliamsDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, 677 Huntington Ave, K501, Boston, MA, 02115, USA.
B Lee PeterlinDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA.
Harvard University · USAsociación Civil Impacta Salud y Educación · PEHarvard Global Health Institute · USHospital del Trabajador · CLJohns Hopkins Medicine · US

Funding

University of Washington MHIRT Training Program GrantT37MD001449 · NIMHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2005 to 2018
$3.5M
A Cohort Study of Preterm Delivery in Relation to Partner Abuse, Mood and AnxietyR01HD059835 · NICHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2010 to 2014
$2.8M
NICHD NIH HHS R01 HD059835NIMHD NIH HHS T37 MD001449
6 · The paper itself

Abstract

backgroundIndividually both migraine and post-traumatic stress disorder (PTSD) prevalence estimates are higher among women. However, there is limited data on the association of migraine and PTSD in women during pregnancy.

methodsWe examined the association between migraine and PTSD among women attending prenatal clinics in Peru. Migraine was characterized using the International Classification of Headache Disorders (ICHD)-III beta criteria. PTSD was assessed using the PTSD Checklist-Civilian Version (PCL-C). Multivariable logistic regression analyses were performed to estimate odds ratios (OR) and 95% confidence intervals (CI) after adjusting for confounders.

resultsOf the 2922 pregnant women included, 33.5% fulfilled criteria for any migraine (migraine 12.5%; probable migraine 21.0%) and 37.4% fulfilled PTSD criteria. Even when controlling for depression, women with any migraine had almost a 2-fold increased odds of PTSD (OR: 1.97; 95% CI: 1.64-2.37) as compared to women without migraine. Specifically, women with migraine alone (i.e. excluding probable migraine) had a 2.85-fold increased odds of PTSD (95% CI: 2.18-3.74), and women with probable migraine alone had a 1.61-fold increased odds of PTSD (95% CI: 1.30-1.99) as compared to those without migraine, even after controlling for depression. In those women with both migraine and comorbid depression, the odds of PTSD in all migraine categories were even further increased as compared to those women without migraine.

conclusionIn a cohort of pregnant women, irrespective of the presence or absence of depression, the odds of PTSD is increased in those with migraine. Our findings suggest the importance of screening for PTSD, specifically in pregnant women with migraine.

Indexed as

AdolescentAdultCohort StudiesComorbidityCross-Sectional StudiesDepressionFemaleHumansMigraine DisordersPeruPregnancyPrevalenceRisk FactorsStress Disorders, Post-TraumaticYoung AdultMigrainePost-traumatic stress disorderPregnancyPTSD

Identifiers

PMID28685258
PMCPMC5500599
OpenAlexW2725079855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.